← Statins × cardiovascular events

SynthesisThe Cochrane database of systematic reviews2013

Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery.

Robert D Sanders et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 188 people · 2013

Range includes no effect

No clear effect on cardiovascular events

−53%−85% to +52%

Bigger than 9 in 10 for cardiovascular events

As reported

RR 0.47, 95% CI 0.15–1.52

Range includes no effect

No clear effect on adverse events & safety

0.9×0.2× to 3.6×

Bigger than 2 in 10 for adverse events & safety

As reported

RR 0.94, 95% CI 0.24–3.63

Range includes no effect

No clear effect on deaths

−27%−69% to +75%

Bigger than 8 in 10 for all-cause mortality

As reported

RR 0.73, 95% CI 0.31–1.75 · the paper's word: All-cause mortality

Three numbers in the abstract

the abstract, start to end

… a non-significant decrease in risk (RR 0.73, 95% CI 0.31 to 1.75).

… a non-significant decrease in risk (RR 0.47, 95% CI 0.15 to 1.52).

… between statin users and controls (RR 0.94, 95% CI 0.24 to 3.63).

← favours treatmentfavours comparator →
could be chance
All-cause mortality
RR 0.730.31–1.75
Cardiovascular events
RR 0.470.15–1.52
Adverse events & safety
RR 0.940.24–3.63
StatinsCardiovascular eventsAll-cause mortalityAdverse events & safety

Statins × cardiovascular eventshelps?replicated

unlikelylikely
0.86not counted

Statins × adverse events & safetyharms?mixed

unlikelylikely
0.16not counted
← favours treatmentfavours comparator →
more certainless certain
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Full record →Abstract, authors, funding and every citing paper · PMID 23824754