ArticleJournal of Korean medical science2013
Small increases in plasma sodium are associated with higher risk of mortality in a healthy population.
Article in Journal of Korean medical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Total Water Intake and Periodontitis in Korean Adults: Evidence from a Nationally Representative Survey.Oral health & preventive dentistry · 2026Article
- Serum sodium, tonicity, and risk of dementia in cohort and healthcare populations.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Serum sodium within the normal range and its U-shaped relationship with biological aging in U.S. adults.Frontiers in nutrition · 2025Article
- Long-term health outcomes associated with hydration status.Nature reviews. Nephrology · 2024Review
- Middle-age high normal serum sodium as a risk factor for accelerated biological aging, chronic diseases, and premature mortality.EBioMedicine · 2023Article
- Serum sodium on admission affects postoperative in-hospital mortality in acute aortic dissection patients.PloS one · 2021Observational
- Cross-Sectional Positive Association of Serum Lipids and Blood Pressure With Serum Sodium Within the Normal Reference Range of 135-145 mmol/L.Arteriosclerosis, thrombosis, and vascular biology · 2017Article
- Article
- Elevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis.PloS one · 2015Article
- Sodium-chloride Difference and Metabolic Syndrome: A Population-based Large-scale Cohort Study.Internal medicine (Tokyo, Japan)Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Elevated blood pressure (BP) is the most common cause of cardiovascular disease. Salt intake has a strong influence on BP, and plasma sodium (pNa) is increased with progressive increases in salt intake. However, the associations with pNa and BP had been reported inconsistently. We evaluated the association between pNa and BP, and estimated the risks of all-cause-mortality according to pNa levels. On the basis of data collected from health checkups during 1995-2009, 97,009 adult subjects were included. Positive correlations between pNa and systolic BP, diastolic BP, and pulse pressure (PP) were noted in participants with pNa ≥138 mM/L (P<0.001). In participants aged ≥50 yr, SBP, DBP, and PP were positively associated with pNa. In participants with metabolic syndrome components, the differences in SBP and DBP according to pNa were greater (P<0.001). A cumulative incidence of mortality was increased with increasing pNa in women aged ≥50 yr during the median 4.2-yr-follow-up (P<0.001). In women, unadjusted risks for mortality were increased according to sodium levels. After adjustment, pNa ≥145 mM/L was related to mortality. The positive correlation between pNa and BP is stronger in older subjects, women, and subjects with metabolic syndrome components. The incidence and adjusted risks of mortality increase with increasing pNa in women aged ≥50 yr.
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