Statins × all-cause mortality

TrialJournal of clinical hypertension (Greenwich, Conn.)2013

Long-term follow-up of moderately hypercholesterolemic hypertensive patients following randomization to pravastatin vs usual care: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT).

Karen L Margolis et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 10,355 people · 2013

Range includes no effect

No clear effect on deaths

−4%−11% to +3%

Bigger than 2 in 10 for all-cause mortality

As reported

HR 0.96, 95% CI 0.89–1.03 · the paper's word: All-cause mortality

One number in the abstract

the abstract, start to end

vs usual care (hazard ratio [HR], 0.96; 95% confidence interval [CI],

← favours treatmentfavours comparator →
could be chance
All-cause mortality
HR 0.960.89–1.03
StatinsAll-cause mortality

Statins × all-cause mortalityhelps?mixed

unlikelylikely
0.500.50 without it
← favours treatmentfavours comparator →
this papermore certainless certain
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Full record →Abstract, authors, funding and every citing paper · PMID 23889716