Trial reportJournal of diabetes science and technology2013
Evaluation of the performance of a novel system for continuous glucose monitoring.
Trial report in Journal of diabetes science and technology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 54 citations in OpenAlex.
- Analyzing the Potential of Advanced Insulin Dosing Strategies in Patients With Type 2 Diabetes: Results From a Hybrid In Silico Study.Journal of diabetes science and technology · 2018Trial
- Use of microdialysis-based continuous glucose monitoring to drive real-time semi-closed-loop insulin infusion.Journal of diabetes science and technology · 2014Trial
- Accuracy of a novel noninvasive transdermal continuous glucose monitor in critically ill patients.Journal of diabetes science and technology · 2014Trial
- Impact of Bindarit, a CCL2 Chemokine Synthesis Inhibitor, on Macrophage-Based Biofouling and Continuous Glucose MonitoringBiosensors & bioelectronics: X · 2024Article
- Accuracy of FreeStyle Libre flash glucose monitoring in patients with type 2 diabetes who migrated from highlands to plains.World journal of diabetes · 2024Article
- Clinical Performance Evaluation of Continuous Glucose Monitoring Systems: A Scoping Review and Recommendations for Reporting.Journal of diabetes science and technology · 2023Article
- Continuous glucose monitoring for automatic real-time assessment of eating events and nutrition: a scoping review.Frontiers in nutrition · 2023Article
- Magneto-Mechanically Triggered Thick Films for Drug Delivery Micropumps.Nanomaterials (Basel, Switzerland) · 2022Article
- Validity of continuous glucose monitoring for categorizing glycemic responses to diet: implications for use in personalized nutrition.The American journal of clinical nutrition · 2022Article
- Benefits and Limitations of MARD as a Performance Parameter for Continuous Glucose Monitoring in the Interstitial Space.Journal of diabetes science and technology · 2020Article
- Performance and Usability of Three Systems for Continuous Glucose Monitoring in Direct Comparison.Journal of diabetes science and technology · 2019Article
- Limits to the Evaluation of the Accuracy of Continuous Glucose Monitoring Systems by Clinical Trials.Biosensors · 2018Article
- Crosslinked basement membrane-based coatings enhance glucose sensor function and continuous glucose monitoring in vivo.Journal of biomedical materials research. Part A · 2018Article
- Effect of BGM Accuracy on the Clinical Performance of CGM: An In-Silico Study.Journal of diabetes science and technology · 2017Article
- Extensive Assessment of Blood Glucose Monitoring During Postprandial Period and Its Impact on Closed-Loop Performance.Journal of diabetes science and technology · 2017Article
- A Review of the Current Challenges Associated with the Development of an Artificial Pancreas by a Double Subcutaneous Approach.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2017Review
- Analysis of the Accuracy and Performance of a Continuous Glucose Monitoring Sensor Prototype: An In-Silico Study Using the UVA/PADOVA Type 1 Diabetes Simulator.Journal of diabetes science and technology · 2017Article
- Significance and Reliability of MARD for the Accuracy of CGM Systems.Journal of diabetes science and technology · 2017Article
- Impact of CCL2 and CCR2 chemokine/receptor deficiencies on macrophage recruitment and continuous glucose monitoring in vivo.Biosensors & bioelectronics · 2016Article
- Accuracy of Continuous Glucose Monitoring in Patients After Total Pancreatectomy with Islet Autotransplantation.Diabetes technology & therapeutics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe performance of a continuous glucose monitoring (CGM) system in the early stage of development was assessed in an inpatient setting that simulates daily life conditions of people with diabetes. Performance was evaluated at low glycemic, euglycemic, and high glycemic ranges as well as during phases with rapid glucose excursions.
methodsEach of the 30 participants with type 1 diabetes (15 female, age 47 ± 12 years, hemoglobin A1c 7.7% ± 1.3%) wore two sensors of the prototype system in parallel for 7 days. Capillary blood samples were measured at least 16 times per day (at least 15 times per daytime and at least once per night). On two subsequent study days, glucose excursions were induced. For performance evaluation, the mean absolute relative difference (MARD) between CGM readings and paired capillary blood glucose readings and precision absolute relative difference (PARD), i.e., differences between paired CGM readings were calculated.
resultsOverall aggregated MARD was 9.2% and overall aggregated PARD was 7.5%. During induced glucose excursions, MARD was 10.9% and PARD was 7.8%. Lowest MARD (8.5%) and lowest PARD (6.4%) were observed in the high glycemic range (euglycemic range, MARD 9.1% and PARD 7.4%; low glycemic range, MARD 12.3% and PARD 12.4%).
conclusionsThe performance of this prototype CGM system was, particularly in the hypoglycemic range and during phases with rapid glucose fluctuations, better than performance data reported for other commercially available systems. In addition, performance of this prototype sensor was noticeably constant over the whole study period. This prototype system is not yet approved, and performance of this CGM system needs to be further assessed in clinical studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.