Trial reportClinics (Sao Paulo, Brazil)2013
Exercise prescription using the heart of claudication pain onset in patients with intermittent claudication.
Trial report in Clinics (Sao Paulo, Brazil), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- A systematic review of exercise intervention reporting quality and dose in studies of intermittent claudication.Vascular · 2023Pooled it
- Safety of home-based exercise for people with intermittent claudication: A systematic review.Vascular medicine (London, England) · 2022Pooled it
- Intensity-dependent effects of exercise therapy on walking performance and aerobic fitness in symptomatic patients with lower-extremity peripheral artery disease: A systematic review and meta-analysis.Vascular medicine (London, England) · 2022Pooled it
- Pooled it
- Supervised exercise therapy versus home-based exercise therapy versus walking advice for intermittent claudication.The Cochrane database of systematic reviews · 2018Pooled it
- Exercise for intermittent claudication.The Cochrane database of systematic reviews · 2017Pooled it
- Pooled it
- Exercise training for management of peripheral arterial disease: a systematic review and meta-analysis.Sports medicine (Auckland, N.Z.) · 2015Pooled it
- Walking Training Improves Ambulatory Blood Pressure Variability in Claudication.Arquivos brasileiros de cardiologia · 2021Trial
- Multidisciplinary Formulation of a Walking Rehabilitation Nursing Protocol for Patients with Lower Extremity Arteriosclerosis Obliterans: A Delphi Study.Journal of multidisciplinary healthcare · 2026Article
- Supervised exercise training improves cardiorespiratory fitness and reduces perioperative risk in peripheral artery disease patients with intermittent claudication.Annals of the Royal College of Surgeons of England · 2024Article
- Physiological Responses to Maximal and Submaximal Walking in Patients with Symptomatic Peripheral Artery Disease.Arquivos brasileiros de cardiologia · 2021Article
- Walking Training Improve Ambulatorial Blood Pressure Variability in Claudicants.Arquivos brasileiros de cardiologia · 2021Article
- Location of ischemia and ischemic pain intensity affect spatiotemporal parameters and leg muscles activity during walking in patients with intermittent claudication.Scientific reports · 2021Article
- Skeletal muscle capillary density is related to anaerobic threshold and claudication in peripheral artery disease.Vascular medicine (London, England) · 2020Article
- Peripheral arterial disease: Scoping review of patient-centred outcomes.International wound journal · 2019Article
- Exercise Intensity during 6-Minute Walk Test in Patients with Peripheral Artery Disease.Arquivos brasileiros de cardiologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the acute metabolic and cardiovascular responses to walking exercise at an intensity corresponding to the heart rate of claudication pain onset and to investigate the effects of a 12-week walking training program at this intensity on walking capacity.
methodsTwenty-nine patients with intermittent claudication were randomly allocated to the walking training (n=17) or control (CO, n=12) group. The walking training group performed an acute exercise session comprising 15×2-min bouts of walking at the heart rate of claudication pain onset, with 2-min interpolated rest intervals. The claudication symptoms and cardiovascular and metabolic responses were evaluated. Walking training was then performed at the same intensity twice each week for 12 weeks, while the control group engaged in twice weekly stretching classes. The claudication onset distance and total walking distance were evaluated before and after the interventions. Brazilian Registry Clinical Trials: RBR-7M3D8W.
resultsDuring the acute exercise session, the heart rate was maintained within tight limits. The exercise intensity was above the anaerobic threshold and >80% of the heart rate peak and VO2peak. After the exercise training period, the walking exercise group (n=13) showed increased claudication onset distance (309±153 vs. 413±201m) and total walking distance (784±182 vs. 1,100±236m) compared to the control group (n=12) (p<0.05).
conclusionWalking exercise prescribed at the heart rate of claudication pain onset enables patients with intermittent claudication to exercise with tolerable levels of pain and improves walking performance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.