ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2013
The prognostic value of transient ischemic dilatation with otherwise normal SPECT myocardial perfusion imaging: a cautionary note in patients with diabetes and coronary artery disease.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic and prognostic significance of transient ischemic dilation (TID) in myocardial perfusion imaging: A systematic review and meta-analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Pooled it
- Prognostic value of heart rate response during regadenoson stress myocardial perfusion imaging in patients with end stage renal disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Trial
- Relationship between left ventricular cavity size and transient ischaemic dilation ratio on dipyridamole stress single-photon emission computerized tomography myocardial perfusion imaging in a female Asian population.European heart journal. Imaging methods and practice · 2025Article
- Prognostic value of transient ischemic dilatation byAnnals of nuclear medicine · 2025Article
- Impact of change of ischemic burden on the outcomes of ESRD patients awaiting kidney transplantation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Myocardial ischemia in patients with large prior infarction: Clinical decision making and review of literature.Radiology case reports · 2023Article
- The prognostic implications of ST-segment and T-wave abnormalities in patients undergoing regadenoson stress SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- The diagnostic accuracy of stress myocardial perfusion scintigraphy in patients with end-stage renal disease.American journal of cardiovascular disease · 2021Article
- Transient ischaemic dilation and post-stress wall motion abnormality increase risk in patients with less than moderate ischaemia: analysis of the REFINE SPECT registry.European heart journal. Cardiovascular Imaging · 2020Article
- Is left ventricular systolic index the new kid in the block?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Evaluation of Myocardial Perfusion Imaging SPECT Parameters and Pharmacologic Stress Test with Adenosine Versus Coronary Angiography Findings: Are They Diagnostically Concordant?Molecular imaging and radionuclide therapy · 2019Article
- The significance of post-stress decrease in left ventricular ejection fraction in patients undergoing regadenoson stress gated SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Transient ischemic dilation: An old but not obsolete marker of extensive coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Deciding wisely: A case for an effective use of myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- Computer derived transient ischemic dilation ratio for identifying extensive coronary artery disease using a CZT camera and imaging in the upright position.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Normal limits for transient ischemic dilation withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Stress SPECT Myocardial Perfusion Imaging in End-Stage Renal Disease.Current cardiovascular imaging reports · 2017Article
- The prognostic value of regadenoson SPECT myocardial perfusion imaging in patients with end-stage renal disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Prognostic value of transient ischemic dilation with regadenoson myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Prognostic impact of TID in regadenoson MPI: Some patients and certain events.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prognostic implications of transient ischemic dilatation (TID) of the left ventricle with otherwise normal single-photon emission computed tomography myocardial perfusion imaging (MPI) remain controversial. Whether this finding may have prognostic implications only in high-risk populations, such as patients with diabetes or manifest coronary artery disease (CAD), is uncertain.
methodsWe conducted a prospective cohort study of 1,236 consecutive patients with normal (99m)Tc-sestamibi MPI, defined as normal perfusion (summed stress score = 0) and normal left ventricle volume and function. TID was defined as >2 standard deviations above the mean of patients with low likelihood of CAD.
resultsThe study subjects were followed for 27 ± 9 months. The 76 (6%) patients with TID had a greater rate of cardiac death or myocardial infarction (MI) [4 (5.3%) vs 11 (0.6%), P = .003] independent of covariates [hazard ratio = 6.4, P = .004]. This finding was entirely derived from the subgroup of 294 patients with diabetes or CAD [4 (13.3%) with TID vs 1 (0.4%) without TID, P = .001] independent of covariates. However, TID was not predictive of cardiac death or MI among the 941 patients without diabetes or CAD. Furthermore, TID was not predictive of coronary revascularization.
conclusionsThis study confirms a benign prognosis of TID with otherwise normal MPI in patients without diabetes or CAD, but cautions against extending this conclusion to high-risk individuals, particularly those with diabetes or CAD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.