Metformin × glycemic control

TrialClinical drug investigation2013

Saxagliptin add-on therapy to insulin with or without metformin for type 2 diabetes mellitus: 52-week safety and efficacy.

Anthony H Barnett et al.PubMed ↗Publisher ↗

What the trial testedrandomised · 455 people · 2013

Randomised comparison

Probably lowered glycemic control

−0.37percentage points−0.55 to −0.19

As reported

difference −0.37 %, 95% CI −0.55 to −0.19

One number in the abstract

the abstract, start to end

adjusted between-group difference was -0.37 % (95 % CI -0.55 to -0.19);

← favours treatmentfavours comparator →
could be chance
Glycemic control
−0.37−0.55 to −0.19
MetforminGlycemic control

Metformin × glycemic controlhelps?replicated

unlikelylikely
0.840.84 without it
← favours treatmentfavours comparator →
this papermore certainless certain
1 / 5

19 papers cite it

2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
this paperpooled ittrialcites it
Full record →Abstract, authors, funding and every citing paper · PMID 23949898