← Other lipid agents × lipids

SynthesisCirculation2013

Levels and changes of HDL cholesterol and apolipoprotein A-I in relation to risk of cardiovascular events among statin-treated patients: a meta-analysis.

S Matthijs Boekholdt et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation, not cause

Went with fewer cardiovascular events

−17%−19% to −14%

Bigger than 4 in 10 for cardiovascular events

As reported

HR 0.83, 95% CI 0.81–0.86

Correlation, not cause

Went with fewer cardiovascular events

−21%−28% to −18%

Bigger than 5 in 10 for cardiovascular events

As reported

HR 0.79, 95% CI 0.72–0.82

Correlation · may be no link

No clear link with lipids

−2%−6% to +1%

Smaller than almost all on the map

As reported

HR 0.98, 95% CI 0.94–1.01

+1 more in the walkthrough ↓

Four numbers in the abstract

the abstract, start to end

… events (adjusted hazard ratio [HR], 0.83; 95% confidence interval [CI], 0.81-0.86 per 1 standard deviation increment), as were apoA-I levels (HR, 0.79; 95% CI, 0.72-0.82).

… with reduced cardiovascular risk (HR, 0.98; 95% CI, 0.94-1.01 per 1 standard deviation increment), whereas a rise in apoA-I was (HR, 0.93; 95% CI, 0.90-0.97).

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
HR 0.830.81–0.86
Cardiovascular events
HR 0.790.72–0.82
Lipids
HR 0.980.94–1.01
Lipids
HR 0.930.90–0.97
Other lipid agentsLipidsCardiovascular events
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