ArticleBMC genomics2013
Physiological change under OsHV-1 contamination in Pacific oyster Crassostrea gigas through massive mortality events on fields.
Article in BMC genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Dynamics of the transcriptomic landscape of OsHV-1 replication in haemocytes of the Pacific oyster (The Journal of general virology · 2025Article
- Exploring the Potential of Metatranscriptomics to Describe Microbial Communities and Their Effects in Molluscs.International journal of molecular sciences · 2022Article
- Genomic associations with poxvirus across divergent island populations in Berthelot's pipit.Molecular ecology · 2022Article
- Pooled resequencing of larvae and adults reveals genomic variations associated with Ostreid herpesvirus 1 resistance in the Pacific oysterFrontiers in immunology · 2022Article
- The Pacific Oyster Mortality Syndrome, a Polymicrobial and Multifactorial Disease: State of Knowledge and Future Directions.Frontiers in immunology · 2021Review
- High temperature induces transcriptomic changes inThe Journal of experimental biology · 2020Article
- Immune Control of Herpesvirus Infection in Molluscs.Pathogens (Basel, Switzerland) · 2020Review
- Article
- Exploring First Interactions Between Ostreid Herpesvirus 1 (OsHV-1) and Its Host,Frontiers in microbiology · 2019Article
- The Voltage-Dependent Anion Channel (VDAC) of Pacific Oysters Crassostrea gigas Is Upaccumulated During Infection by the Ostreid Herpesvirus-1 (OsHV-1): an Indicator of the Warburg Effect.Marine biotechnology (New York, N.Y.) · 2018Article
- Article
- Infectious diseases in oyster aquaculture require a new integrated approach.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Infectious diseases of marine molluscs and host responses as revealed by genomic tools.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Occurrence of OsHV-1 inFrontiers in physiology · 2016Article
- GigaTON: an extensive publicly searchable database providing a new reference transcriptome in the pacific oyster Crassostrea gigas.BMC bioinformatics · 2015Article
- Cell Walls and the Convergent Evolution of the Viral Envelope.Microbiology and molecular biology reviews : MMBR · 2015Review
- Dual transcriptomics of virus-host interactions: comparing two Pacific oyster families presenting contrasted susceptibility to ostreid herpesvirus 1.BMC genomics · 2014Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMassive mortalities have been observed in France since 2008 on spat and juvenile Pacific oysters, Crassostrea gigas. A herpes virus called OsHV-1, easily detectable by PCR, has been implicated in the mortalities as demonstrated by the results of numerous field studies linking mortality with OsHV-1 prevalence. Moreover, experimental infections using viral particles have documented the pathogenicity of OsHV-1 but the physiological responses of host to pathogen are not well known.
resultsThe aim of this study was to understand mechanisms brought into play against the virus during infection in the field. A microarray assay has been developed for a major part of the oyster genome and used for studying the host transcriptome across mortality on field. Spat with and without detectable OsHV-1 infection presenting or not mortality respectively were compared by microarray during mortality episodes. In this study, a number of genes are regulated in the response to pathogen infection on field and seems to argue to an implication of the virus in the observed mortality. The result allowed establishment of a hypothetic scheme of the host cell's infection by, and response to, the pathogen.
conclusionsThis response shows a "sensu stricto" innate immunity through genic regulation of the virus OsHV-1 life cycle, but also others biological processes resulting to complex interactions between host and pathogens in general.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.