Evidence map›Paper›PMID 24003303›Full record

ReviewClinical ophthalmology (Auckland, N.Z.)2013

Current and emerging treatment options for uveal melanoma.

Patricia Rusa Pereira, Alexandre Nakao Odashiro, Li-Anne Lim, Cristina Miyamoto, Paula L Blanco, Macanori Odashiro, Shawn Maloney, Dominique F De Souza, Miguel N Burnier

Abstract readReview
In one paragraph

Review in Clinical ophthalmology (Auckland, N.Z.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Highly tumoricidal efficiency of non-oxidized MXene-TiFrontiers in bioengineering and biotechnology · 2022
    Article
  11. Article
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  19. Uveal melanoma: progress in molecular biology and therapeutics.Therapeutic advances in medical oncology · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patricia Rusa PereiraThe Henry C Witelson Ocular Pathology Laboratory, McGill University, Montreal, QC, Canada.
Alexandre Nakao Odashiro
Li-Anne Lim
Cristina Miyamoto
Paula L Blanco
Macanori Odashiro
Shawn Maloney
Dominique F De Souza
Miguel N Burnier

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uveal melanoma (UM) is the most common primary malignant intraocular tumor in adults, with a 10-year cumulative metastatic rate of 34%. The most common site of metastasis is the liver (95%). Unfortunately, the current treatment of metastatic UM is limited by the lack of effective systemic therapy. Options for the management of the primary intraocular tumor include radical surgery as well as conservative treatments in order to preserve visual acuity. For metastatic disease, several approaches have been described with no standard method. Nevertheless, median survival after liver metastasis is poor, being around 4-6 months, with a 1-year survival of 10%-15%. In this review, the authors summarize current and promising new treatments for UM.

Indexed as

choroidal melanomaeyemetastasistherapytreatmentuveal melanoma

Identifiers

PMID24003303
PMCPMC3755706

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.