Evidence map›Paper›PMID 24022207›Full record

ReviewPharmacoEconomics2013

Antiplatelet therapy in patients undergoing percutaneous coronary intervention: economic considerations.

William S Weintraub, Leonid Mandel, Sandra A Weiss

Abstract readComparative StudyReview
In one paragraph

Review in PharmacoEconomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Antithrombotic therapy in adults with ectatic coronary artery disease: a systematic review and network meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Building the Case for Clopidogrel as a World Health Organization Essential Medicine.Circulation. Cardiovascular quality and outcomes · 2015
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

William S Weintraub
Leonid Mandel
Sandra A Weiss
Christiana Care Health System · US

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Gregory E Hicks · 2013 to 2026
$60.5M
X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 1985 to 2007
$21.3M
Robotic Exoskeletons, FES, and Biomechanics: Treating Movement DisordersR01HD038582 · NICHD · UNIVERSITY OF DELAWARE · PI BINDER-MACLEOD, STUART A. · 2002 to 2012
$6.1M
LONGITUDINAL FOLLOW UP AND EXTENSION OF JOINT ATTENTION INTERVENTIONU19HD035470 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SIGMAN, MARIAN D · 2002 to 2006
$4.0M
Fast Treadmill Training/Functional Electrical Stimulation to Improve WalkingR01NR010786 · NINR · UNIVERSITY OF DELAWARE · PI BINDER-MACLEOD, STUART A. · 2007 to 2011
$2.8M
HIV/AIDS RISK REDUCTION AMONG DRUG INVOLVED PROBATIONERSR01DA011611 · NIDA · UNIVERSITY OF DELAWARE · PI MARTIN, STEVEN S · 1999 to 2003
$2.4M
TARGETED INVESTIGATION OF DISTAL XQ IN RETT SYNDROMER01HD037874 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SCHANEN, N. CAROLYN · 2000 to 2010
$2.3M
FORCE OPTIMIZATION IN SKELETAL MUSCLER01HD036797 · NICHD · UNIVERSITY OF DELAWARE · PI BINDER-MACLEOD, STUART A. · 1998 to 2005
$1.5M
DVD-based HIV/HCV Intervention for Drug-Involved Latino Criminal Justice ClientsR34DA031063 · NIDA · UNIVERSITY OF DELAWARE · PI IBANEZ, GLADYS EULALIA, MARTIN, STEVEN S · 2012 to 2014
$611k
NCRR NIH HHS M01 RR000039NICHD NIH HHS R01 HD036797NICHD NIH HHS R01 HD037874NICHD NIH HHS R01 HD038582NICHD NIH HHS U19 HD035470NIDA NIH HHS R01 DA011611NIDA NIH HHS R34 DA031063NIGMS NIH HHS U54 GM104941NINR NIH HHS R01 NR010786
6 · The paper itself

Abstract

Percutaneous coronary intervention (PCI) is one of the most common medical procedures performed for treatment of coronary artery disease. Antiplatelet medications as adjunctive therapy for PCI are used routinely, with indications for specific agents or their combinations varying depending on the clinical scenario. While the cost-effectiveness of well-established agents has been extensively studied, newer drugs have not been evaluated as thoroughly. In addition, the clinical application of some antiplatelet drugs has recently changed, thus making older studies of cost effectiveness less applicable to the current landscape of clinical practice. This article reviews cost-effectiveness considerations of antiplatelet therapies in the treatment of coronary artery disease in patients undergoing PCI. Aspirin, P2Y12 inhibitors including clopidogrel and the newer agents prasugrel and ticagrelor, as well as glycoprotein (GP) IIb/IIIa inhibitors, are discussed. Overall, the use of dual antiplatelet therapy with aspirin and a P2Y12 inhibitor in patients undergoing PCI improves ischaemic outcomes and appears to be cost effective. The few available studies suggest that the recently approved medications prasugrel and ticagrelor are cost-effective alternatives to clopidogrel. However, no direct comparison between these two newer agents is available. The indications for GP IIb/IIIa inhibitors have changed in the current PCI era, and there is a paucity of cost-effectiveness data for their use in contemporary care.

Indexed as

AspirinCoronary Artery DiseaseCost-Benefit AnalysisDrug Therapy, CombinationHumansPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexTreatment OutcomeAspirinPlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa Complex

Identifiers

PMID24022207
PMCPMC4816975
OpenAlexW1990954455

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.