SynthesisThe Cochrane database of systematic reviews2013
Surveillance of gastric intestinal metaplasia for the prevention of gastric cancer.
Synthesis in The Cochrane database of systematic reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- AGA Technical Review on Gastric Intestinal Metaplasia-Epidemiology and Risk Factors.Gastroenterology · 2020Pooled it
- Gastric cancer in patients with gastric atrophy and intestinal metaplasia: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Gastric Cancer Risk in Patients with Intestinal Metaplasia: Long-Term Outcomes from a Large Single-Center Cohort in Türkiye.Journal of clinical medicine · 2025Article
- Revisiting X-linked agammaglobulinemia.Journal of human immunity · 2025Review
- Translating evidence into action: overcoming barriers to gastric cancer prevention in Aotearoa.Journal of the Royal Society of New Zealand · 2025Review
- Revealing the pathogenesis of gastric intestinal metaplasia based on the mucosoid air-liquid interface.Journal of translational medicine · 2024Article
- Identifying the pre-malignant stomach: from guidelines to practice.Translational gastroenterology and hepatology · 2022Review
- Micronutrient Food Supplements in Patients with Gastro-Intestinal and Hepatic Cancers.International journal of molecular sciences · 2021Review
- Do non-targeted gastric biopsies affect the management of patients, and can a simple protocol and education reduce the rate?Frontline gastroenterology · 2018Article
- Low yield for non-targeted biopsies of the stomach and esophagus during elective esophagogastroduodenoscopy.Endoscopy international open · 2017Article
- Diagnosis and Management of Upper Gastrointestinal Neuroendocrine Tumors.Clinical endoscopy · 2017Review
- hTERT promotes gastric intestinal metaplasia by upregulating CDX2 via NF-κB signaling pathway.Oncotarget · 2017Article
- Helicobacter pylori associated gastric intestinal metaplasia: Treatment and surveillance.World journal of gastroenterology · 2016Review
- Endoscopic surveillance of gastrointestinal premalignant lesions: current knowledge and future directions.Current opinion in gastroenterology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdenocarcinoma of the stomach is the second leading cause of cancer related death in the world. Gastric intestinal metaplasia (GIM) is a recognised premalignant condition of the stomach. It has been described as occurring in up to one in five patients in western countries. Although there is a definite risk of progression from GIM to cancer, published guidelines and statements differ as to the utility and structure of surveillance programs for this condition.
objectivesTo see whether or not endoscopic or biochemical surveillance of patients with gastric intestinal metaplasia (GIM) could result in increased detection of dysplasia and early gastric cancer to decrease gastric cancer mortality. SEARCH
methodsWe performed a search of the following electronic databases from inception to October 2012: CENTRAL, EMBASE, MEDLINE and LILACS. We handsearched for abstracts from relevant conferences. SELECTION CRITERIA: Randomised controlled trials only were included. DATA COLLECTION AND ANALYSIS: No studies met the inclusion criteria. MAIN
resultsNo studies met the inclusion criteria. AUTHORS'
conclusionsThere is a lack of randomised data on the utility of surveillance of GIM. The observational data from non-randomised studies are discussed and would suggest that although a randomised trial would be a desirable undertaking to attain the highest grade of clinical evidence, given the ethical and acceptability issues involved, further non-randomised clinical studies focussing on surveillance protocols and the role of Helicobacter pylori eradication may be a more pragmatic means of addressing the core clinical question.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.