Evidence map›Paper›PMID 24077237›Full record

ReviewNutrients2013

Polyphenols: benefits to the cardiovascular system in health and in aging.

Sandhya Khurana, Krishnan Venkataraman, Amanda Hollingsworth, Matthew Piche, T C Tai

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03372109 (A Randomized Controlled Trial to Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain in Overweight But Generally Healthy Adults Over the Winter Holiday Period), which is not on this map. Cited by 167 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 4 pooled it
21.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03372109 nacompletednot on this mapstarted 2017, after this paper: background citation

A Randomized Controlled Trial to Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain in Overweight But Generally Healthy Adults Over the Winter Holiday Period

TypeinterventionalSponsorSupplement Formulators, Inc.Ran2017 to 2018Enrolled23ConditionsBody Weight ChangesArmsMeal replacement shake, Multivitamin and mineral capsules, Fish oil with sesame lignans and olive extract softgel, Prebiotic Chewable tablet, Clove Extract and Maqui Berry extract capsule
3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 4 syntheses or guidelines pooled it, 422 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Dietary polyphenols in prevention and treatment of prostate cancer.International journal of molecular sciences · 2015
    Pooled it
  5. Trial
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  8. Effects ofMolecules (Basel, Switzerland) · 2026
    Article
  9. Acute Effects ofFoods (Basel, Switzerland) · 2026
    Article
  10. Functional Evaluation of Pomegranate (Antioxidants (Basel, Switzerland) · 2026
    Article
  11. Review
  12. Review
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  15. Review
  16. Article
  17. Review
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  20. Article

107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sandhya KhuranaMedical Sciences Division, Northern Ontario School of Medicine, Sudbury, ON P3E 2C6, Canada. tc.tai@nosm.ca.
Krishnan Venkataraman
Amanda Hollingsworth
Matthew Piche
T C Tai
NOSM University · CAHuntington University · CALaurentian University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have demonstrated the importance of naturally occurring dietary polyphenols in promoting cardiovascular health and emphasized the significant role these compounds play in limiting the effects of cellular aging. Polyphenols such as resveratrol, epigallocatechin gallate (EGCG), and curcumin have been acknowledged for having beneficial effects on cardiovascular health, while some have also been shown to be protective in aging. This review highlights the literature surrounding this topic on the prominently studied and documented polyphenols as pertaining to cardiovascular health and aging.

Indexed as

AgingAnimalsCardiovascular SystemCatechinCurcuminDietDisease Models, AnimalFruitHeart DiseasesHumansOlive OilPlant OilsPolyphenolsQuercetinRandomized Controlled Trials as TopicReactive Oxygen SpeciesCatechinCurcuminepigallocatechin gallateOlive OilPlant OilsPolyphenolsQuercetinReactive Oxygen SpeciesResveratrolStilbenes

Identifiers

PMID24077237
PMCPMC3820045
OpenAlexW2108128042

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.