ReviewMusculoskeletal surgery2014
Sarcopenia and its relationship with osteoarthritis: risk factor or direct consequence?
Review in Musculoskeletal surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05019820 (Identification of Sarcopenia in Knee Osteoarthritis With Ultrasonography and Evaluation of Muscle Architecture Change by Ultrasonography After Isokinetic Exercise Program), which is not on this map. Cited by 37 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identification of Sarcopenia in Knee Osteoarthritis With Ultrasonography and Evaluation of Muscle Architecture Change by Ultrasonography After Isokinetic Exercise Program
Who cites it
37 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of sarcopenia on clinical outcomes of older adults undergoing total knee arthroplasty for osteoarthritis: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Effects of upper extremity blood flow restriction training on muscle strength and hypertrophy: a systematic review and meta-analysis.Frontiers in physiology · 2024Pooled it
- Biomechanical and neural changes evaluation induced by prolonged use of non-stable footwear: a systematic review.Musculoskeletal surgery · 2015Pooled it
- Trial
- Anterior cruciate ligament reconstruction and return to sport activity: postural control as the key to success.International orthopaedics · 2015Trial
- Sarcopenia: current state of knowledge and its implications in orthopaedics and traumatology for enhanced clinical strategies and patient outcomes.Musculoskeletal surgery · 2026Review
- MRI-based radiomics to determine the role of thigh muscle quality in the development of knee osteoarthritis: A discovery and validation study.Journal of advanced research · 2026Article
- Higher Prevalence of Sarcopenia in Knee Osteoarthritis and Its Association with Femoral Intercondylar Cartilage Thickness and Functional Outcomes.Life (Basel, Switzerland) · 2025Article
- Deep Learning-Based Automatic Muscle Segmentation of the Thigh Using Lower Extremity CT Images.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Article
- Relationship Between Sarcopenia, Femoral Cartilage Thickness, and Knee Osteoarthritis: Case-Control Study.International journal of rheumatic diseases · 2025Article
- Examining the Relationship Between Sarcopenia and Rotator Cuff Tears: A Retrospective Comparative Study.Journal of clinical medicine · 2025Article
- ChatGPT-4 and wearable device assisted Intelligent Exercise Therapy for co-existing Sarcopenia and Osteoarthritis (GAISO): a feasibility study and design for a randomized controlled PROBE non-inferiority trial.Journal of orthopaedic surgery and research · 2024Article
- Effects of blood flow restriction therapy in patients with knee osteoarthritis: protocol for an overview of systematic reviews.Frontiers in rehabilitation sciences · 2024Review
- Bioinformatics and systems biology approaches to identify potential common pathogeneses for sarcopenia and osteoarthritis.Frontiers in medicine · 2024Article
- Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension.Cartilage · 2023Article
- Does Sarcopenia Accompanying End-Stage Knee Osteoarthritis Affect the Outcomes following Total Knee Arthroplasty?Medicina (Kaunas, Lithuania) · 2023Article
- Association of a femoral neck T score with knee joint osteophyte formation but not with skeletal muscle mass.Clinical rheumatology · 2023Article
- Prevalence of Sarcopenia in Knee Osteoarthritis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this review is to evaluate the clinical role of sarcopenia in patients affected by osteoarthritis (OA) of major joints.
methodsAn online database research was performed, in order to retrieve all articles investigating the relationship between sarcopenia and OA. No peer-reviewed journal was excluded. Papers in English, French, Spanish and Italian language were considered. After consulting the full-text article, five studies have been included in the review.
resultsOf the five studies included, four are prospective studies and only one is a cross-sectional study which retrieved data retrospectively. A total of 4,231 patients, presenting a mean age of 62.0 years, were studied. Three studies evaluated only female subjects. Weight, height and body mass index were reported in all the articles. Knee OA has been assessed using the Kellgren-Lawrence grading system and the American college of rheumatology criteria. Alterations of the lean body mass on body weight ratio have been reported to be as a significant predictive parameter in two studies. Relationship between radiographic OA and an increase in the leg lean mass has been observed in one study.
conclusionsWe cannot support neither the thesis of a direct effect of sarcopenia on OA development nor the opposite relation, because the up-to-date literature lacks basic science studies concerning these topics. The absence of clinical studies regarding measurements and tools to compare sarcopenia and OA do not allow to definitely clarify this relationship.
Indexed as
Identifiers
24482109What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.