Evidence map›Paper›PMID 24567110›Full record

ReviewJournal of mammary gland biology and neoplasia2014

Lipid transport in the lactating mammary gland.

James L McManaman

Abstract readReview
In one paragraph

Review in Journal of mammary gland biology and neoplasia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Animals : an open access journal from MDPI · 2026
    Article
  6. Review
  7. Article
  8. Association of Human Milk Fatty Acid Composition with Maternal Cardiometabolic Diseases: An Exploratory Prospective Cohort Study.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Liver X receptor-α activation enhances cholesterol secretion in lactating mammary epithelium.American journal of physiology. Endocrinology and metabolism · 2019
    Article
  18. Per- and polyfluoroalkyl substances in human breast milk and current analytical methods.Environmental science and pollution research international · 2018
    Review
  19. Milk lipid regulation at the maternal-offspring interface.Seminars in cell & developmental biology · 2018
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

James L McManamanDivision of Basic Reproductive Sciences, University of Colorado School of Medicine, Mail Stop 8613, 12700 E. 19th Ave., Aurora, CO, 80045, USA, jim.mcmanaman@ucdenver.edu.

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
The functional role of microRNAs in the normal mammary glandP01HD038129 · NICHD · UNIVERSITY OF COLORADO DENVER · PI ANDERSON, STEVEN M · 2000 to 2015
$15.2M
MECHANISMS OF MILK LIPID SECRETIONR01HD045965 · NICHD · UNIVERSITY OF COLORADO DENVER · PI MCMANAMAN, JAMES LEWIS · 2004 to 2013
$2.8M
North Carolina Collaborative PPRU NetworkU10HD045962 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2004 to 2009
$2.1M
Postnatal Actions of Maternal Obesity on Neonatal Metabolic HealthR01HD075285 · NICHD · UNIVERSITY OF COLORADO DENVER · PI MACLEAN, PAUL S., MCMANAMAN, JAMES LEWIS · 2013 to 2017
$1.6M
NICHD NIH HHS 1R01-HD075285NICHD NIH HHS 5R01-HD045962NICHD NIH HHS P01 HD038129NICHD NIH HHS P01-HD38129NICHD NIH HHS R01 HD045965NICHD NIH HHS R01 HD075285NICHD NIH HHS U10 HD045962NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

Mammalian cells depend on phospholipid (PL) and fatty acid (FA) transport to maintain membrane structure and organization, and to fuel and regulate cellular functions. In mammary glands of lactating animals, copious milk secretion, including large quantities of lipid in some species, requires adaptation and integration of PL and FA synthesis and transport processes to meet secretion demands. At present few details exist about how these processes are regulated within the mammary gland. However, recent advances in our understanding of the structural and molecular biology of membrane systems and cellular lipid trafficking provide insights into the mechanisms underlying the regulation and integration of PL and FA transport processes the lactating mammary gland. This review discusses the PL and FA transport processes required to maintain the structural integrity and organization of the mammary gland and support its secretory functions within the context of current molecular and cellular models of their regulation.

Indexed as

AnimalsBiological TransportFemaleHumansLactationLipid MetabolismMammary Glands, AnimalMammary Glands, Human

Identifiers

PMID24567110
PMCPMC4413448

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.