SynthesisBMJ clinical evidence2014
Nausea and vomiting in early pregnancy.
Synthesis in BMJ clinical evidence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of acustimulation on nausea and vomiting and on hyperemesis in pregnancy: a systematic review of Western and Chinese literature.BMC complementary and alternative medicine · 2016Pooled it
- A randomized feasibility trial of time-restricted eating during pregnancy in people with increased risk of gestational diabetes.Scientific reports · 2024Trial
- Evaluation of oral health during pregnancy and implementation of maternal oral screening tool and referral process in pregnant women: A cross-sectional study.Journal of family medicine and primary care · 2025Article
- How are hospitals in England, Scotland and Wales caring for women with nausea and vomiting in pregnancy: a national service evaluation.BMC health services research · 2025Article
- Multicenter Cross-Sectional Study of Oral Health and Hygiene Practices Among Pregnant Women.Journal of clinical medicine · 2024Article
- Article
- The Amount of Fluid Intake among Pregnant Women in China Increases with Pregnancy Progression: A Prospective Cohort Study.Nutrients · 2023Article
- Influence of Pregnancy on Sexual Desire in Pregnant Women and Their Partners: Systematic Review.Public health reviews · 2023Review
- Systematic evidence map of evidence addressing the top 10 priority research questions for hyperemesis gravidarum.BMJ open · 2022Article
- Late-Pregnancy Dysglycemia After Negative Testing for Gestational Diabetes and Risk of the Large-for-Gestational-Age Newborns: A Nest Case-Control Study Based on the Xi'an Longitudinal Mother-Child Cohort Study.Frontiers in pediatrics · 2022Article
- Article
- Ginger for nausea and vomiting of pregnancy.Canadian family physician Medecin de famille canadien · 2016Review
- Barriers and Challenges in Hyperemesis Gravidarum Research.Nutrition and metabolic insights · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMore than half of pregnant women suffer from nausea and vomiting, which typically begins by the fourth week and disappears by the 16th week of pregnancy. The cause of nausea and vomiting in pregnancy is unknown, but may be due to the rise in human chorionic gonadotrophin concentration. In 1 in 200 women, the condition progresses to hyperemesis gravidarum, which is characterised by prolonged and severe nausea and vomiting, dehydration, and weight loss. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatment for nausea and vomiting in early pregnancy? What are the effects of treatments for hyperemesis gravidarum? We searched: Medline, Embase, The Cochrane Library, and other important databases up to September 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
resultsWe found 32 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
conclusionsIn this systematic review we present information relating to the effectiveness and safety of the following interventions: acupressure; acupuncture; corticosteroids; ginger; metoclopramide; ondansetron; prochlorperazine; promethazine; and pyridoxine (vitamin B6).
Indexed as
Identifiers
24646807PMC3959188What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.