Evidence map›Paper›PMID 24653003›Full record

ReviewGenetics2014

Resources for functional genomics studies in Drosophila melanogaster.

Stephanie E Mohr, Yanhui Hu, Kevin Kim, Benjamin E Housden, Norbert Perrimon

Abstract readReview
In one paragraph

Review in Genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Genetics of Diabetes: What We Can Learn fromInternational journal of molecular sciences · 2021
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Generating and working with Drosophila cell cultures: Current challenges and opportunities.Wiley interdisciplinary reviews. Developmental biology · 2019
    Review
  13. Insights from intoxicated Drosophila.Alcohol (Fayetteville, N.Y.) · 2019
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Reduced CardiacCirculation. Cardiovascular genetics · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie E MohrDrosophila RNAi Screening Center, Harvard Medical School, Boston, Massachusetts 02115.
Yanhui Hu
Kevin Kim
Benjamin E Housden
Norbert Perrimon

Funding

Tuberous Sclerosis-Pathway and PathogenesisP01CA120964 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI David J. Kwiatkowski · 2007 to 2026
$35.9M
New collections of dsRNAs and overexpression miRNA constructs to supplement RNAiR01GM067761 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI PERRIMON, NORBERT · 2003 to 2019
$15.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
Development of Validated Drosophila in vivo RNAi Models of Human DiseasesR24OD011176 · OD · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2012 to 2014
$1.5M
Development of Validated Drosophila in vivo RNAi Models of Human DiseasesR24RR032668 · NCRR · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2011 to 2011
$440k
NCI NIH HHS P01 CA120964NCRR NIH HHS R24 RR032668NIGMS NIH HHS R01 GM067761NIGMS NIH HHS R01 GM084947NIH HHS R24 OD011176
6 · The paper itself

Abstract

Drosophila melanogaster has become a system of choice for functional genomic studies. Many resources, including online databases and software tools, are now available to support design or identification of relevant fly stocks and reagents or analysis and mining of existing functional genomic, transcriptomic, proteomic, etc. datasets. These include large community collections of fly stocks and plasmid clones, "meta" information sites like FlyBase and FlyMine, and an increasing number of more specialized reagents, databases, and online tools. Here, we introduce key resources useful to plan large-scale functional genomics studies in Drosophila and to analyze, integrate, and mine the results of those studies in ways that facilitate identification of highest-confidence results and generation of new hypotheses. We also discuss ways in which existing resources can be used and might be improved and suggest a few areas of future development that would further support large- and small-scale studies in Drosophila and facilitate use of Drosophila information by the research community more generally.

Indexed as

AnimalsDatabases, GeneticDrosophila melanogasterGenetic EngineeringGenome, InsectGenomicsHumansbioinformaticscommunity resourcesDrosophila: functional genomicsonline tools

Identifiers

PMID24653003
PMCPMC4012471

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.