Evidence map›Paper›PMID 24672442›Full record

ReviewFrontiers in behavioral neuroscience2014

Endogenous peripheral oxytocin measures can give insight into the dynamics of social relationships: a review.

Catherine Crockford, Tobias Deschner, Toni E Ziegler, Roman M Wittig

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in behavioral neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
22.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it, 180 citations in OpenAlex.

  1. Pooled it
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  12. How does oxytocin modulate human behavior?Molecular psychiatry · 2025
    Review
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  20. Thermal imaging reveals social monitoring during social feeding in wild chimpanzees.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Catherine CrockfordDepartment of Primatology, Max Planck Institute for Evolutionary Anthropology Leipzig, Germany.
Tobias DeschnerDepartment of Primatology, Max Planck Institute for Evolutionary Anthropology Leipzig, Germany.
Toni E ZieglerWisconsin National Primate Research Center, University of Wisconsin Madison, WI, USA.
Roman M WittigDepartment of Primatology, Max Planck Institute for Evolutionary Anthropology Leipzig, Germany.
Max Planck Institute for Evolutionary Anthropology · DEUniversity of Wisconsin–Madison · US

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
NIH HHS P51 OD011106
6 · The paper itself

Abstract

The neuropeptide, oxytocin, receives increasing attention due to its role in stress regulation and promoting affiliative social behavior. Research across mammals points to a complex pattern whereby social context and individual differences moderate the central release of oxytocin as well as moderate the effects that exogenous administration of oxytocin has on social behavior. In addition, it is becoming evident that measuring endogenous peripheral oxytocin levels is an informative tool. This is particularly so when oxytocin can be measured from non-invasively collected samples, such as in urine. Although it is still debated as to whether peripheral measures of oxytocin relate to central measures of oxytocin, anatomical and functional evidence indicate a link between the two. We argue that non-invasive measures of peripheral oxytocin hold several research and potential therapeutic advantages. Principally, study subjects can be sampled repeatedly in different social contexts where social history between interaction partners can be taken into account. Several hormones can be measured simultaneously allowing examination of the influence of oxytocin interactions with other hormones on motivational states. Valence of relationships as well as changes in relationship quality over time can be measured through endocrine responses. Also, the approach of identifying natural social contexts that are associated with endogenous oxytocin release offers the potential of behavioral therapy as an addition or alternative to chemical therapy in the field of mental health.

Indexed as

cooperationendogenous peripheral oxytocinmulti-hormone samplingnon-invasive samplingsocial bondssocial interaction dynamics

Identifiers

PMID24672442
PMCPMC3949137
OpenAlexW2157920552

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.