ArticleGenetics2014
The lengths of admixture tracts.
Article in Genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed.
- Characterizing features of the genetic architecture underlying autism from a multi-ancestry perspective.Molecular psychiatry · 2026Article
- Enhancement of hidden Markov model analyses for improved inference of archaic introgression in modern humans.Molecular biology and evolution · 2026Article
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- Deep learning reveals genomic regions introgressed between two recurrently hybridizing lynx species.Molecular biology and evolution · 2026Article
- Recovering signatures of archaic introgression using ancestral recombination graphs.bioRxiv : the preprint server for biology · 2026Article
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
- Analytical expectations for ancestry junction accumulation in admixed genomes.bioRxiv : the preprint server for biology · 2025Article
- Admixed and single-continental genome segments of the same ancestry have distinct linkage disequilibrium patterns.Genome biology · 2025Article
- Leveraging Whole Genomes, Mitochondrial DNA and Haploblocks to Decipher Complex Demographic Histories: An Example From a Broadly Admixed Arctic Fish.Molecular ecology · 2025Article
- Towards Reliable Detection of Introgression in the Presence of Among-Species Rate Variation.Systematic biology · 2024Article
- Understanding admixture fractions: theory and estimation of gene-flow.Journal of mathematical biology · 2024Article
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- Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations.Nature communications · 2024Article
- The temporal and genomic scale of selection following hybridization.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Reconstructing complex admixture history using a hierarchical model.Briefings in bioinformatics · 2024Article
- A general approach for inferring the ancestry of recent ancestors of an admixed individual.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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- Temporal Variation in Introgressed Segments' Length Statistics Computed from a Limited Number of Ancient Genomes Sheds Light on Past Admixture Pulses.Molecular biology and evolution · 2023Article
- Methods for Assessing Population Relationships and History Using Genomic Data.Annual review of genomics and human genetics · 2023Review
- On the number of genealogical ancestors tracing to the source groups of an admixed population.Genetics · 2023Article
13 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
The distribution of admixture tract lengths has received considerable attention, in part because it can be used to infer the timing of past gene flow events between populations. It is commonly assumed that these lengths can be modeled as independently and identically distributed (iid) exponential random variables. This assumption is fundamental for many popular methods that analyze admixture using hidden Markov models. We compare the expected distribution of admixture tract lengths under a number of population-genetic models to the distribution predicted by the Wright-Fisher model with recombination. We show that under the latter model, the assumption of iid exponential tract lengths does not hold for recent or for ancient admixture events and that relying on this assumption can lead to false positives when inferring the number of admixture events. To further investigate the tract-length distribution, we develop a dyadic interval-based stochastic process for generating admixture tracts. This representation is useful for analyzing admixture tract-length distributions for populations with recent admixture, a scenario in which existing models perform poorly.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.