Evidence map›Paper›PMID 24794262›Full record

ReviewOral and maxillofacial surgery clinics of North America2014

Epidemiologic trends in head and neck cancer and aids in diagnosis.

Nadarajah Vigneswaran, Michelle D Williams

Open access · greenAbstract readReview
In one paragraph

Review in Oral and maxillofacial surgery clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 427 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
427citing papers in PubMed, 5 pooled it
12.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

427 citing papers in PubMed, 5 syntheses or guidelines pooled it, 815 citations in OpenAlex.

  1. Prognostic Significance of the Pretreatment Neutrophil-to-Lymphocyte Ratio and Tumor-Associated Neutrophils in Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta-Analysis.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2026
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  10. Oral microbiota associated with radiation-related caries among nasopharyngeal carcinoma patients following radiation therapy: analysis based on a longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  11. Perceived Discrimination Among Patients With Head and Neck Cancer.Laryngoscope investigative otolaryngology · 2026
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  12. Review
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  15. International journal of molecular sciences · 2026
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367 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nadarajah VigneswaranOral and Maxillofacial Pathology Biopsy Service, The University of Texas School of Dentistry at Houston, 1941 East Road BBSB, Room 5320, Houston, TX 77054, USA. Electronic address: nadarajah.vigneswaran@uth.tmc.edu.
Michelle D WilliamsSurgical Pathology Fellowship Program, Head & Neck Section, Department of Pathology, UT MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit #085, Houston, TX 77030, USA.
The University of Texas at Austin · USThe University of Texas MD Anderson Cancer Center · US

Funding

Aptamer mediated targeting of Fanconi Anemia oral cancer initiating cellsR01DE024392 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ANNAPRAGADA, ANANTH V, VIGNESWARAN, NADARAJAH · 2014 to 2017
$1.5M
Targeted Liposomal Delivery of CD147 siRNA to Murine Head and Neck Cancer ModelsR21DE019956 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI VIGNESWARAN, NADARAJAH · 2009 to 2010
$410k
NIDCR NIH HHS R01 DE024392NIDCR NIH HHS R21 DE019956
6 · The paper itself

Abstract

Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic determination. Clinical biomarkers are still needed to improve early detection, predict malignant transformation, and optimize therapies.

Indexed as

Biomarkers, TumorCarcinoma, Squamous CellCell Transformation, NeoplasticDiagnostic ImagingHead and Neck NeoplasmsHumansIncidenceMouth DiseasesOropharyngeal NeoplasmsPapillomaviridaePredictive Value of TestsRisk FactorsTobacco Use DisorderBiomarkers, TumorDiagnosisEpidemiologic trendsHead and neck cancerSquamous cell carcinomas

Identifiers

PMID24794262
PMCPMC4040236
OpenAlexW2110435930

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.