Evidence map›Paper›PMID 24840980›Full record

ReviewNature immunology2014

Post-transcriptional coordination of immunological responses by RNA-binding proteins.

Panagiota Kafasla, Antonis Skliris, Dimitris L Kontoyiannis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 193 citations in OpenAlex.

  1. Review
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  10. Review
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  13. Review
  14. Review
  15. Article
  16. RNA Metabolism Governs Immune Function and Response.Advances in experimental medicine and biology · 2024
    Review
  17. Article
  18. Article
  19. Article
  20. Article

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Panagiota KafaslaDivision of Immunology, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
Antonis SklirisDivision of Immunology, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
Dimitris L KontoyiannisDivision of Immunology, Biomedical Sciences Research Center "Alexander Fleming", Vari, Greece.
Alexander Fleming Biomedical Sciences Research Center · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunological reactions are propelled by ever-changing signals that alter the translational ability of the RNA in the cells involved. Such alterations are considered to be consequential modifications in the transcriptomic decoding of the genetic blueprint. The identification of RNA-binding protein (RBP) assemblies engaged in the coordinative regulation of state-specific RNAs indicates alternative and exclusive means for determining the activation, plasticity and tolerance of cells of the immune system. Here we review current knowledge about RBP-regulated post-transcriptional events involved in the reactivity of cells of the immune system and the importance of their alteration during chronic inflammatory pathology and autoimmunity.

Indexed as

RNA Processing, Post-TranscriptionalAnimalsAutoimmunityHumansImmune ToleranceImmunity, CellularInflammationLymphocyte ActivationLymphopoiesisMiceRegulatory Sequences, Ribonucleic AcidRNA-Binding ProteinsRNA, MessengerSignal TransductionRegulatory Sequences, Ribonucleic AcidRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID24840980
OpenAlexW1978251557

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.