Evidence map›Paper›PMID 24843701›Full record

ArticleJournal of diabetes investigation2013

Effect of periodontal treatment on glycemic control of patients with diabetes: A systematic review and meta-analysis.

Stefano Corbella, Luca Francetti, Silvio Taschieri, Francesca De Siena, Massimo Del Fabbro

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02874963 (Impact of Combined Non-surgical and Surgical Periodontal Treatment in Patients With Type 2 Diabetes Mellitus), which is not on this map. Cited by 41 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 11 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02874963 naunknown statusnot on this mapstarted 2015, after this paper: background citation

Impact of Combined Non-surgical and Surgical Periodontal Treatment in Patients With Type 2 Diabetes Mellitus

TypeinterventionalSponsorUniversity Clinical Centre of KosovaRan2015 to 2016Enrolled160ConditionsPeriodontitis, Type 2 Diabetes MellitusArmsSurgical Periodontal Treatment, Non Surgical Periodontal Treatment includes scaling root planing with UDS-J Ultrasonic Scaler., Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%)
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 11 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Article
  14. Review
  15. Review
  16. Article
  17. Periodontal Diseases and Diabetes Mellitus: A Systematic Review.Journal of pharmacy & bioallied sciences · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stefano CorbellaDepartment of Biomedical, Surgical and Dental Sciences Oral Implantology Research Center Università degli Studi di Milano IRCCS Istituto Ortopedico Galeazzi Milan Italy.
Luca FrancettiDepartment of Biomedical, Surgical and Dental Sciences Oral Implantology Research Center Università degli Studi di Milano IRCCS Istituto Ortopedico Galeazzi Milan Italy ; Department of Biomedical, Surgical and Dental Sciences Oral Health Research Center Università degli Studi di Milano IRCCS Istituto Ortopedico Galeazzi Milan Italy.
Silvio TaschieriDepartment of Biomedical, Surgical and Dental Sciences Oral Health Research Center Università degli Studi di Milano IRCCS Istituto Ortopedico Galeazzi Milan Italy.
Francesca De SienaDepartment of Biomedical, Surgical and Dental Sciences Oral Health Research Center Università degli Studi di Milano IRCCS Istituto Ortopedico Galeazzi Milan Italy.
Massimo Del FabbroDepartment of Biomedical, Surgical and Dental Sciences Oral Implantology Research Center Università degli Studi di Milano IRCCS Istituto Ortopedico Galeazzi Milan Italy ; Department of Biomedical, Surgical and Dental Sciences Oral Health Research Center Università degli Studi di Milano IRCCS Istituto Ortopedico Galeazzi Milan Italy.
Istituto Ortopedico Galeazzi · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AIMS/

introductionThe aim of the present study was to investigate whether non-surgical periodontal treatment reduces glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) levels in diabetic patients. MATERIALS AND

methodsAn electronic search was carried out on MEDLINE (through PubMed interface), EMBASE and the Cochrane Central Register of Controlled Trials. Randomized controlled trials with a minimum of 3 months follow up were included. The risk of bias was assessed for each study. A meta-analysis was carried out to evaluate the effect of non-surgical periodontal treatment on HbA1c and FPG levels. The effect of the adjunctive use of antimicrobials was also assessed.

resultsA total of 15 studies were included. A reduction of -0.38% (95% confidence interval [CI] -0.23 to -0.53) after 3-4 months (P < 0.001) and of -0.31% (95% CI 0.11 to -0.74) after 6 months (P = 0.15) of follow-up was found for HbA1c, favoring the treatment group. Similarly, in treated patients, a significantly greater decrease in FPG was observed in respect to control participants. Such difference amounted to -9.01 mg/dL (95% CI -2.24 to -15.78) after 3-4 months (P = 0.009) and -13.62 mg/dL (95% CI 0.45 to -27.69) after 6 months (P = 0.06) from treatment, respectively. In participants treated with adjunctive antimicrobials, a non-significant increase of HbA1c was observed 3 months after treatment, whereas FPG decreased by 0.27 mg/dL (95% CI 39.56 to -40.11; P = 0.99).

conclusionsThe meta-analysis showed that non-surgical periodontal treatment improves metabolic control in patients with both periodontitis and diabetes.

Indexed as

DiabetesMetabolic controlPeriodontal diseases

Identifiers

PMID24843701
PMCPMC4025114
OpenAlexW2055734875

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.