Evidence map›Paper›PMID 24869934›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2014

Carotid artery intima-media thickness and erectile dysfunction in patients with metabolic syndrome.

Mustafa Unal, Duygu Yazgan Aksoy, Yusuf Aydın, Mine Durusu Tanriover, Dilek Berker, Jale Karakaya, Serdar Guler

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. The effect of stress on testosterone and sexual function.International journal of impotence research · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Lower urinary tract symptoms, erectile dysfunction, and their correlation in men aged 50 years and above: a cross-sectional survey in Beijing, China.Medical science monitor : international medical journal of experimental and clinical research · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mustafa UnalDepartment of Endocrinology and Metabolism, Numune Research and Training Hospital, Ankara, Turkey.
Duygu Yazgan Aksoyepartment of Endocrinology and Metabolism, Numune Research and Training Hospital, Ankara, Turkey.
Yusuf AydınDepartment of Internal Medicine, Section of Endocrinology and Metabolism, Duzce University, Duzce, Turkey.
Mine Durusu TanrioverDepartment of Internal Medicine, Section of General Internal Medicine, Hacettepe University, Ankara, Turkey.
Dilek BerkerDepartment of Endocrinology and Metabolism, Numune Research and Training Hospital, Ankara, Turkey.
Jale KarakayaDepartment of Biostatistics, Hacettepe University, Ankara, Turkey.
Serdar GulerDepartment of Endocrinology and Metabolism, Numune Research and Training Hospital, Ankara, Turkey.
Ankara Numune Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolic syndrome (MS) has become a pandemic in Turkey, as is the case globally. Increase in carotid artery intima-media thickness (CIMT) and erectile dysfunction (ED) may be evident before the clinical signs of cardiovascular disease appear. We aimed to investigate the prevalence of increased CIMT and ED as markers of atherosclerotic disease in patients with MS. MATERIAL AND

methodsThirty-two patients with MS and 29 healthy controls were included. Anthropometric and biochemical parameters, along with total testosterone (TT), high sensitive C-reactive protein (hs-CRP), were recorded. Carotid artery intima-media thickness was measured. Erectile dysfunction was assessed with International Index of Erectile Function.

resultsPatients with MS had higher BMI, fasting plasma glucose, post-prandial plasma glucose, insulin, HOMA-IR, total cholesterol, triglycerides, hs-CRP, and CIMT, whereas TT levels were lower (p<0.0001). The prevalence and severity of erectile dysfunction were higher in patients with MS (p<0.0001). Erectile dysfunction scores correlated inversely with CIMT. MS patients with ED were older and had higher CIMT compared to those without ED. Increase in age and HOMA and decrease in TT increased the risk of ED. When KIMT exceeding the 95th percentile of healthy controls was accepted as a risk factor for CVD, presence of ED was the only determinant for this increase.

conclusionsErectile dysfunction was more prevalent and severe in patients with MS and correlated with subclinical endothelial dysfunction. Total testosterone deficiency was prominent among MS patients. Presence of ED points to an increased risk of cardiovascular disease when MS is present.

Indexed as

Carotid Intima-Media ThicknessAdultDemographyErectile DysfunctionHumansMaleMetabolic Syndrome

Identifiers

PMID24869934
PMCPMC4049947
OpenAlexW2056638459

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.