Evidence map›Paper›PMID 24907422›Full record

ReviewCurrent opinion in microbiology2014

Induced antiviral innate immunity in Drosophila.

Olivier Lamiable, Jean-Luc Imler

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. TheProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Immune Control of Herpesvirus Infection in Molluscs.Pathogens (Basel, Switzerland) · 2020
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Gypsy moth genome provides insights into flight capability and virus-host interactions.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  19. Article
  20. International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Olivier LamiableCNRS-UPR9022, Institut de Biologie Moléculaire et Cellulaire, 15 rue Descartes, F-67084 Strasbourg, France.
Jean-Luc ImlerCNRS-UPR9022, Institut de Biologie Moléculaire et Cellulaire, 15 rue Descartes, F-67084 Strasbourg, France; Faculté des Sciences de la Vie, Université de Strasbourg, 28 rue Goethe, F-67083 Strasbourg, France. Electronic address: JL.Imler@unistra.fr.
Centre National de la Recherche Scientifique · FRInstitut de Biologie Moléculaire et Cellulaire · FR

Funding

Sequencing CoreP01AI070167 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI BEUTLER, BRUCE A · 2006 to 2016
$27.2M
NIAID NIH HHS P01 AI070167
6 · The paper itself

Abstract

Immunity to viral infections in the model organism Drosophila melanogaster involves both RNA interference and additional induced responses. The latter include not only cellular mechanisms such as programmed cell death and autophagy, but also the induction of a large set of genes, some of which contribute to the control of viral replication and resistance to infection. This induced response to infection is complex and involves both virus-specific and cell-type specific mechanisms. We review here recent developments, from the sensing of viral infection to the induction of signaling pathways and production of antiviral effector molecules. Our current understanding, although still partial, validates the Drosophila model of antiviral induced immunity for insect pests and disease vectors, as well as for mammals.

Indexed as

Host-Pathogen InteractionsImmunity, InnateAnimalsDrosophila melanogasterGene Expression RegulationRNA VirusesSignal Transduction

Identifiers

PMID24907422
PMCPMC4133299
OpenAlexW1979017239

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.