Evidence map›Paper›PMID 24926308›Full record

ArticleDementia and geriatric cognitive disorders extra2014

Decreased motor function is associated with poorer cognitive function in elderly with type 2 diabetes.

Elizabeth Guerrero-Berroa, Ramit Ravona-Springer, Anthony Heymann, James Schmeidler, Jeremy M Silverman, Mary Sano, Keren Koifmann, Rachel Preiss, Hadas Hoffman, Michal Schnaider Beeri

Abstract read
In one paragraph

Article in Dementia and geriatric cognitive disorders extra, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elizabeth Guerrero-BerroaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA.
Ramit Ravona-SpringerThe Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, USA.
Anthony HeymannMaccabi Healthcare Services, University of Tel Aviv, Tel-Aviv, Israel ; Sackler Faculty of Medicine, University of Tel Aviv, Tel-Aviv, Israel.
James SchmeidlerDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA.
Jeremy M SilvermanDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA ; James J. Peters Veterans Affairs Medical Center, Bronx, N.Y., USA.
Mary SanoDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA ; James J. Peters Veterans Affairs Medical Center, Bronx, N.Y., USA.
Keren KoifmannThe Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, USA.
Rachel PreissMaccabi Healthcare Services, University of Tel Aviv, Tel-Aviv, Israel.
Hadas HoffmanMaccabi Healthcare Services, University of Tel Aviv, Tel-Aviv, Israel.
Michal Schnaider BeeriDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA ; The Joseph Sagol Neuroscience Center, Sheba Medical Center, Ramat Gan, USA.

Funding

VESICULAR LOCALIZATION AND FUNCTION OF PRESENILIN 1 FRAGMENTP50AG005138 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GROSSMAN, HILLEL · 1985 to 2019
$37.9M
Inflammation, long-term diabetes characteristics, and cognitive declineR01AG034087 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCHNAIDER BEERI, MICHAL · 2009 to 2014
$3.7M
NIA NIH HHS P50 AG005138NIA NIH HHS R01 AG034087
6 · The paper itself

Abstract

BACKGROUND/

aimsImpaired motor function has been associated with cognitive impairment and dementia, but this relationship is poorly understood in elderly with type 2 diabetes (T2D). We thus investigated it in a large sample (n = 726) of cognitively normal elderly with T2D.

methodsIn this cross-sectional study, hierarchical linear regressions assessed correlations of 3 motor measures (timed walk, grip strength, and self-reported motor difficulties) with episodic memory, attention/working memory, semantic categorization, executive function, and overall cognition controlling for demographics.

resultsLonger timed walk and weaker grip strength were associated with poorer performance in all cognitive domains except episodic memory.

conclusionsAssociations of motor and cognitive functions in T2D and non-T2D samples are consistent. A lack of association of motor function with episodic memory may suggest non-Alzheimer's disease-related underlying mechanisms.

Indexed as

CognitionDementiaElderlyMemoryMotor functionType 2 diabetes

Identifiers

PMID24926308
PMCPMC4036126

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.