ReviewFrontiers in genetics2014
Longevity pathways and memory aging.
Review in Frontiers in genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- Mitochondrial aconitase 1 regulates age-related memory impairment via autophagy/mitophagy-mediated neural plasticity in middle-aged flies.Aging cell · 2021Article
- The Emerging Role of Sestrin2 in Cell Metabolism, and Cardiovascular and Age-Related Diseases.Aging and disease · 2020Review
- Common Protective Strategies in Neurodegenerative Disease: Focusing on Risk Factors to Target the Cellular Redox System.Oxidative medicine and cellular longevity · 2020Review
- Effect ofEvidence-based complementary and alternative medicine : eCAM · 2019Article
- A role for autophagy in long-term spatial memory formation in male rodents.Journal of neuroscience research · 2018Article
- Differential Regulation of Hippocampal IGF-1-Associated Signaling Proteins by Dietary Restriction in Aging Mouse.Cellular and molecular neurobiology · 2017Article
- Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017Article
- Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects.Nature communications · 2017Article
- Genetic Analysis of Mitochondrial Ribosomal Proteins and Cognitive Aging in Postmenopausal Women.Frontiers in genetics · 2017Article
- Article
- mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging.Annals of the New York Academy of Sciences · 2015Review
- Alzheimer's patient feedback to complement research using model systems for cognitive aging and dementia.Frontiers in genetics · 2014Article
- Arabidopsis mTERF15 is required for mitochondrial nad2 intron 3 splicing and functional complex I activity.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aging process has been associated with numerous pathologies at the cellular, tissue, and organ level. Decline or loss of brain functions, including learning and memory, is one of the most devastating and feared aspects of aging. Learning and memory are fundamental processes by which animals adjust to environmental changes, evaluate various sensory signals based on context and experience, and make decisions to generate adaptive behaviors. Age-related memory impairment is an important phenotype of brain aging. Understanding the molecular mechanisms underlying age-related memory impairment is crucial for the development of therapeutic strategies that may eventually lead to the development of drugs to combat memory loss. Studies in invertebrate animal models have taught us much about the physiology of aging and its effects on learning and memory. In this review we survey recent progress relevant to conserved molecular pathways implicated in both aging and memory formation and consolidation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.