Evidence map›Paper›PMID 24943285›Full record

Trial reportJournal of human hypertension2014

Effects of a DASH-like diet containing lean beef on vascular health.

M A Roussell, A M Hill, T L Gaugler, S G West, J S Ulbrecht, J P Vanden Heuvel, P J Gillies, P M Kris-Etherton

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of human hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 4 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

M A RoussellDepartment of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.
A M HillDepartment of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.
T L GauglerDepartment of Statistics, Pennsylvania State University, University Park, PA, USA.
S G West1] Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA [2] Department of Biobehavioral Health, Pennsylvania State University, University Park, PA, USA.
J S Ulbrecht1] Department of Biobehavioral Health, Pennsylvania State University, University Park, PA, USA [2] Department of Medicine, Pennsylvania State University, University Park, PA, USA.
J P Vanden HeuvelDepartment of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA, USA.
P J GilliesNew Jersey Institute for Food, Nutrition and Health, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA.
P M Kris-EthertonDepartment of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA.
Pennsylvania State University · USCarnegie Mellon University · USRutgers, The State University of New Jersey · US

Funding

WRITING AND THE DAILY EXPERIENCE OF ILLNESSM01RR010732 · NCRR · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI PAZ, HAROLD L. · 1995 to 2009
$29.8M
NCRR NIH HHS M01 RR010732NCRR NIH HHS M01RR10732
6 · The paper itself

Abstract

A DASH (dietary approaches to stop hypertension) dietary pattern rich in fruits and vegetables and low-fat dairy products with increased dietary protein provided primarily from plant protein sources decreases blood pressure. No studies, however, have evaluated the effects of a DASH-like diet with increased dietary protein from lean beef on blood pressure and vascular health. The aim of this study was to study the effect of DASH-like diets that provided different amounts of protein from lean beef (DASH 28 g beef per day; beef in an optimal lean diet (BOLD) 113 g beef per day; beef in an optimal lean diet plus additional protein (BOLD+) 153 g beef per day) on blood pressure, endothelial function and vascular reactivity versus a healthy American diet (HAD). Using a randomized, crossover study design, 36 normotensive participants (systolic blood pressure (SBP), 116 ± 3.6 mm Hg) were fed four isocaloric diets,: HAD (33% total fat, 12% saturated fatty acids (SFA), 17% protein (PRO), 20 g beef per day), DASH (27% total fat, 6% SFA, 18% PRO, 28 g beef per day), BOLD (28% total fat, 6% SFA, 19% PRO, 113 g beef per day) and BOLD+ (28% total fat, 6% SFA, 27% PRO, 153 g beef per day), for 5 weeks. SBP decreased (P<0.05) in subjects on the BOLD+ diet (111.4 ± 1.9 mm Hg) versus HAD (115.7 ± 1.9). There were no significant effects of the DASH and BOLD diets on SBP. Augmentation index (AI) was significantly reduced in participants on the BOLD diet (-4.1%). There were no significant effects of the dietary treatments on diastolic blood pressure or endothelial function (as measured by peripheral arterial tonometry). A moderate protein DASH-like diet including lean beef decreased SBP in normotensive individuals. The inclusion of lean beef in a heart healthy diet also reduced peripheral vascular constriction.

Indexed as

MeatAdultAgedAged, 80 and overAnimalsCattleCross-Over StudiesEndothelium, VascularFemaleHumansHypertensionMaleMiddle AgedVascular Stiffness

Identifiers

PMID24943285
PMCPMC4160562
OpenAlexW2021816707

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.