Evidence map›Paper›PMID 24955816›Full record

ArticlePublic health nutrition2015

Validation of a BMI cut-off point to predict an adverse cardiometabolic profile with adiposity measurements by dual-energy X-ray absorptiometry in Guatemalan children.

Olga Redondo, Eduardo Villamor, Javiera Valdés, Usama Bilal, Benjamín Caballero, Dina Roche, Fernanda Kroker, Manuel Ramírez-Zea, Manuel Franco

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in Public health nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Olga Redondo1Social and Cardiovascular Epidemiology Research Group,School of Medicine,University of Alcalá,Alcalá de Henares,Madrid 28871,Spain.
Eduardo Villamor3Department of Epidemiology,School of Public Health,University of Michigan,Ann Arbor,MI,USA.
Javiera Valdés4Department of Public Health, Medical Faculty,Catholic University of the North,Santiago de Chile,Chile.
Usama Bilal1Social and Cardiovascular Epidemiology Research Group,School of Medicine,University of Alcalá,Alcalá de Henares,Madrid 28871,Spain.
Benjamín Caballero6Center for Human Nutrition,Department of International Health,Johns Hopkins Bloomberg School of Public Health,Baltimore,MD,USA.
Dina Roche7INCAP Comprehensive Center for the Prevention of Chronic Diseases (CIIPEC),Institute of Nutrition of Central America and Panama (INCAP),Guatemala 1188,Central America.
Fernanda Kroker7INCAP Comprehensive Center for the Prevention of Chronic Diseases (CIIPEC),Institute of Nutrition of Central America and Panama (INCAP),Guatemala 1188,Central America.
Manuel Ramírez-Zea7INCAP Comprehensive Center for the Prevention of Chronic Diseases (CIIPEC),Institute of Nutrition of Central America and Panama (INCAP),Guatemala 1188,Central America.
Manuel Franco1Social and Cardiovascular Epidemiology Research Group,School of Medicine,University of Alcalá,Alcalá de Henares,Madrid 28871,Spain.

Funding

PHS HHS HHSN26820900032C
6 · The paper itself

Abstract

objectiveTo identify a body fat percentage (%BF) threshold related to an adverse cardiometabolic profile and its surrogate BMI cut-off point.

designCross-sectional study.

settingTwo public schools in poor urban areas on the outskirts of Guatemala City. SUBJECTS: A convenience sample of ninety-three healthy, prepubertal, Ladino children (aged 7-12 years).

resultsSpearman correlations of cardiometabolic parameters were higher with %BF than with BMI-for-age Z-score. BMI-for-age Z-score and %BF were highly correlated (r=0·84). The %BF threshold that maximized sensitivity and specificity for predicting an adverse cardiometabolic profile (elevated homeostasis model assessment-insulin resistance index and/or total cholesterol:HDL-cholesterol ratio) according to receiver operating characteristic curve analysis was 36 %. The BMI-for-age Z-score cut-off point that maximized the prediction of BF ≥ 36 % by the same procedure was 1·5. The area under the curve (AUC) for %BF and for BMI data showed excellent accuracy to predict an adverse cardiometabolic profile (AUC 0·93 (sd 0·04)) and excess adiposity (AUC 0·95 (sd 0·02)).

conclusionsSince BMI standards have limitations in screening for adiposity, specific cut-off points based on ethnic-/sex- and age-specific %BF thresholds are needed to better predict an adverse cardiometabolic profile.

Indexed as

AdiposityChild Nutritional Physiological PhenomenaInsulin ResistanceSuburban HealthAbsorptiometry, PhotonBody Mass IndexCardiovascular DiseasesChildChild DevelopmentCross-Sectional StudiesFemaleGuatemalaHumansMaleOverweightPoverty AreasGuatemala

Identifiers

PMID24955816
PMCPMC10271877

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.