Evidence map›Paper›PMID 25006417›Full record

ReviewPulmonary circulation2014

Perioperative pharmacological management of pulmonary hypertensive crisis during congenital heart surgery.

Nathan Brunner, Vinicio A de Jesus Perez, Alice Richter, François Haddad, André Denault, Vanessa Rojas, Ke Yuan, Mark Orcholski, Xiaobo Liao

Abstract readReview
In one paragraph

Review in Pulmonary circulation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Perioperative Management of Pulmonary Hypertension. a Review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Modulation of miRNAs in Pulmonary Hypertension.International journal of hypertension · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Nathan BrunnerDivision of Pulmonary and Critical Care Medicine, Stanford School of Medicine, Stanford, California, USA.
Vinicio A de Jesus PerezDivision of Pulmonary and Critical Care Medicine, Stanford School of Medicine, Stanford, California, USA.
Alice RichterDivision of Pulmonary and Critical Care Medicine, Stanford School of Medicine, Stanford, California, USA.
François HaddadDivision of Cardiology, Stanford School of Medicine, Stanford, California, USA.
André DenaultDivision of Anesthesiology, Montreal Heart Institute, Montreal, Quebec, Canada.
Vanessa RojasDivision of Pulmonary and Critical Care Medicine, Stanford School of Medicine, Stanford, California, USA.
Ke YuanDivision of Pulmonary and Critical Care Medicine, Stanford School of Medicine, Stanford, California, USA.
Mark OrcholskiDivision of Pulmonary and Critical Care Medicine, Stanford School of Medicine, Stanford, California, USA.
Xiaobo LiaoDivision of Pulmonary and Critical Care Medicine, Stanford School of Medicine, Stanford, California, USA ; Division of Cardiothoracic Surgery, Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Stanford Medicine · USMontreal Heart Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertensive crisis is an important cause of morbidity and mortality in patients with pulmonary arterial hypertension secondary to congenital heart disease (PAH-CHD) who require cardiac surgery. At present, prevention and management of perioperative pulmonary hypertensive crisis is aimed at optimizing cardiopulmonary interactions by targeting prostacyclin, endothelin, and nitric oxide signaling pathways within the pulmonary circulation with various pharmacological agents. This review is aimed at familiarizing the practitioner with the current pharmacological treatment for dealing with perioperative pulmonary hypertensive crisis in PAH-CHD patients. Given the life-threatening complications associated with pulmonary hypertensive crisis, proper perioperative planning can help anticipate cardiopulmonary complications and optimize surgical outcomes in this patient population.

Indexed as

congenital heart diseasesperioperative pharmacological therapiespulmonary arterial hypertensionpulmonary hypertensive crisis

Identifiers

PMID25006417
PMCPMC4070760
OpenAlexW2019890804

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.