Evidence map›Paper›PMID 25007882›Full record

ArticleJournal of human genetics2014

No association between Y chromosomal haplogroups and severe acne in the Han Chinese population.

Mei-Hua Guo, Wen-Juan Wu, Long Fan, Min-Sheng Peng, Jian-Kang Yang, Wen Zhang, Fei Hao, Hong-Fu Xie, Lei-Hong Xiang, Min Zheng and 15 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of human genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 16 institutions in 2 countries.

Mei-Hua GuoKunming Medical University, and Institute of Dermatology & Venereology of Yunnan Province, Kunming, China.
Wen-Juan WuKunming Medical University, and Institute of Dermatology & Venereology of Yunnan Province, Kunming, China.
Long FanKIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, China.
Min-Sheng Peng1] KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, China [2] State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Jian-Kang Yang1] State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China [2] Laboratory for Conservation and Utilization of Bio-Resources & Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, China.
Wen Zhang1] KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, China [2] Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Fei HaoDepartment of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Hong-Fu XieDepartment of Dermatology, Xiangya Hospital Central South University, Changsha, China.
Lei-Hong XiangDepartment of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Min ZhengDepartment of Dermatology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Yan-Ni GuoDepartment of Dermatology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Qing-Hua SongDepartment of Dermatology, Peking University Third Hospital, Beijing, China.
Cai-Xia TuDepartment of Dermatology, The Second Hospital of Dalian Medical University, Dalian, China.
Hua ZhongDepartment of Dermatology, Qilu Hospital of Shandong University, Jinan, China.
Wen-Ge FanDepartment of Dermatology, Changshu NO.1 People's Hospital, Changshu, China.
Yue-Jun ShiDepartment of Dermatology, Dalian Dermatosis Hospital, Dalian, China.
Ping CaoDepartment of Dermatology, First people's Hospital of Yunnan Province, Kunming, China.
Lian-Yuan FengYuxi Lianyuan Hospital, Yuxi, China.
Meng NaDepartment of Dermatology, Kaiyuan People's Hospital, Kaiyuan, China.
Qin PangWinona Dermo-Cosmetology Center, Kunming, China.
Xiao-Yan YangWinona Dermo-Cosmetology Center, Kunming, China.
Cheng YangWinona Dermo-Cosmetology Center, Kunming, China.
Xi ZouWinona Dermo-Cosmetology Center, Kunming, China.
Li HeKunming Medical University, and Institute of Dermatology & Venereology of Yunnan Province, Kunming, China.
Ya-Ping Zhang1] KIZ/CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming, China [2] State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China [3] Laboratory for Conservation and Utilization of Bio-Resources & Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan University, Kunming, China.
Winona Medical Cosmetic Center · CNKunming Medical University · CNUniversity of Hong Kong · HKArmy Medical University · CNCentral South University · CNChangshu No.1 People's Hospital · CNChinese Academy of Sciences · CNDalian Dermatosis Hospital · CNDalian Medical University · CNFirst People's Hospital of Yunnan Province · CNFujian Medical University · CNHuashan Hospital · CNPeking University Third Hospital · CNQilu Hospital of Shandong University · CNSecond Affiliated Hospital of Zhejiang University · CNYunnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acne presents sexual dimorphism in its incidence in Chinese population. It is more prevalent in males. To assess the possible Y chromosomal contribution to severe acne risk in Han Chinese males, we analyzed 2041 Y chromosomal SNPs (Y-SNPs) in 725 severe acne cases and 651 controls retrieved from our recent genome-wide association study data. After data filtering, we assigned 585 cases and 494 controls into 12 Y chromosomal haplogroups based on 307 high-confidence Y-SNPs. No statistically significant difference in the distribution of Y chromosomal haplogroup frequencies was observed between the case and control groups. Our results showed a lack of association between the incidence of severe acne and the different Y chromosomal haplogroup in the Han Chinese population.

Indexed as

Acne VulgarisAsian PeopleChromosomes, Human, YGenome-Wide Association StudyHaplotypesHumansMalePolymorphism, Single Nucleotide

Identifiers

PMID25007882
OpenAlexW2039541402

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.