ReviewCurrent diabetes reports2014
Managing sedentary behavior to reduce the risk of diabetes and cardiovascular disease.
Review in Current diabetes reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02377037 (What is the Metabolic Cost of Sitting, Standing, and Sit/Stand Transitions? A Randomized Controlled Trial), which is not on this map. Cited by 78 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
What is the Metabolic Cost of Sitting, Standing, and Sit/Stand Transitions? A Randomized Controlled Trial
Who cites it
78 citing papers in PubMed, 7 syntheses or guidelines pooled it, 177 citations in OpenAlex.
- Pooled it
- Pooled it
- The effectiveness of sedentary behaviour interventions on sitting time and screen time in children and adults: an umbrella review of systematic reviews.The international journal of behavioral nutrition and physical activity · 2020Pooled it
- Interventions outside the workplace for reducing sedentary behaviour in adults under 60 years of age.The Cochrane database of systematic reviews · 2020Pooled it
- Are Office-Based Workplace Interventions Designed to Reduce Sitting Time Cost-Effective Primary Prevention Measures for Cardiovascular Disease? A Systematic Review and Modelled Economic Evaluation.International journal of environmental research and public health · 2019Pooled it
- The energy expenditure benefits of reallocating sedentary time with physical activity: a systematic review and meta-analysis.Journal of public health (Oxford, England) · 2018Pooled it
- Examining sedentary time as a risk factor for cardiometabolic diseases and their markers in South Asian adults: a systematic review.International journal of public health · 2017Pooled it
- The Effects of Standardised versus Individualised Aerobic Exercise Prescription on Fitness-Fatness Index in Sedentary Adults: A Randomised Controlled Trial.Journal of sports science & medicine · 2022Trial
- The effect of 2 walking programs on aerobic fitness, body composition, and physical activity in sedentary office employees.PloS one · 2019Trial
- Interrupting prolonged sitting in type 2 diabetes: nocturnal persistence of improved glycaemic control.Diabetologia · 2017Trial
- Altered extracellular ATP, ADP, and AMP hydrolysis in blood serum of sedentary individuals after an acute, aerobic, moderate exercise session.Molecular and cellular biochemistry · 2017Trial
- Trial
- Effect of frequent interruptions of prolonged sitting on self-perceived levels of energy, mood, food cravings and cognitive function.The international journal of behavioral nutrition and physical activity · 2016Trial
- Trial
- Effectiveness of a walking programme to support adults with intellectual disabilities to increase physical activity: walk well cluster-randomised controlled trial.The international journal of behavioral nutrition and physical activity · 2015Trial
- The associations between sedentary behavior and cognition in a population cohort of older adults.Journal of Alzheimer's disease : JAD · 2026Article
- Machine Learning-Based Prediction Model Construction for Type 2 Diabetes Mellitus: A Comparison of Algorithms and Multilevel Risk Factor Analysis.Journal of diabetes research · 2026Article
- Physical activity and sedentary behavior profiles among prisoners in an open prison: differences in psychological well-being?BMC public health · 2025Article
- Association between the motor optimality score-revised and clinical variables of preterm infants.BMC pediatrics · 2025Article
- Co-producing an intervention to reduce sedentary behaviour in community-dwelling older adults aged ≥ 75 informed by behaviour change theory.BMC geriatrics · 2025Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modern human environments are vastly different from those of our forebears. Rapidly advancing technology in transportation, communications, workplaces, and home entertainment confer a wealth of benefits, but increasingly come with costs to human health. Sedentary behavior-too much sitting as distinct from too little physical activity-contributes adversely to cardiometabolic health outcomes and premature mortality. Findings from observational epidemiology have been synthesized in meta-analyses, and evidence is now shifting into the realm of experimental trials with the aim of identifying novel mechanisms and potential causal relationships. We discuss recent observational and experimental evidence that makes a compelling case for reducing and breaking up prolonged sitting time in both the primary prevention and disease management contexts. We also highlight future research needs, the opportunities for developing targeted interventions, and the potential of population-wide initiatives designed to address too much sitting as a health risk.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.