ReviewWorld journal of gastroenterology2014
Helicobacter pylori and functional dyspepsia: an unsolved issue?
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Burden of intestinal protozoan parasites coinciding with Helicobacter pylori infection in patients with gastrointestinal symptoms.Gut pathogens · 2026Article
- Effects of IntragastricJournal of clinical medicine · 2025Article
- Does helicobacter pylori infection impact reflux symptoms after sleeve gastrectomy? A pilot study using patient reported outcome measures (PROMs).Surgical endoscopy · 2025Article
- Review
- The State of the Art of Molecular Fecal Investigations forInternational journal of molecular sciences · 2023Review
- Role of the duodenal microbiota in functional dyspepsia.Neurogastroenterology and motility · 2022Review
- MODERN APPROACH TO DYSPEPSIA.Acta clinica Croatica · 2021Review
- The Usefulness of Symptom-based Subtypes of Functional Dyspepsia for Predicting Underlying Pathophysiologic Mechanisms and Choosing Appropriate Therapeutic Agents.Journal of neurogastroenterology and motility · 2021Review
- Relationship BetweenInternational journal of general medicine · 2020Article
- Prevention of overuse: A view on upper gastrointestinal endoscopy.World journal of gastroenterology · 2019Review
- Vonoprazan andFrontiers in pharmacology · 2019Review
- A comparison of techniques to address the frequency of Helicobacter pylori positive dyspeptic patient.BMC research notes · 2018Article
- Certain Dietary Habits Contribute to the Functional Dyspepsia in South China Rural Area.Medical science monitor : international medical journal of experimental and clinical research · 2017Article
- Noninvasive molecular analysis ofWorld journal of gastroenterology · 2017Review
- Effects of Proton Pump Inhibitors on the Gastric Mucosa-Associated Microbiota in Dyspeptic Patients.Applied and environmental microbiology · 2016Article
- Functional dyspepsia: new insights into pathogenesis and therapy.The Korean journal of internal medicine · 2016Review
- Effects of Lactobacillus gasseri OLL2716 on Helicobacter pylori-Associated Dyspepsia: A Multicenter Randomized Double-Blind Controlled Trial.Gastroenterology research and practice · 2016Article
- Changing prevalence of Helicobacter pylori infection and peptic ulcer among dyspeptic Sardinian patients.Internal and emergency medicine · 2015Article
- The Comparison of Levofloxacin- and Clarithromycin-Based Bismuth Quadruple Therapy Regimens inJournal of research in pharmacy practiceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with Helicobacter pylori (H. pylori) infection may complain of dyspeptic symptoms without presence of macroscopic lesions on gastroduodenal mucosa. Such a condition is usually recognized as functional dyspepsia, and different pathogenetic mechanisms are involved. The role of H. pylori in these patients is controversial. Several trials assessed the potential role of H. pylori eradication in improving dyspeptic symptoms, and data of some meta-analyses demonstrated that cure of infection is associated with a small (10%), but significant therapeutic gain as compared to placebo. The reason for which dyspeptic symptoms regress in some patients following bacterial eradication, but persist in others remains unclear. Regrettably, trials included in the meta-analyses are somewhat different for study design, definition of symptoms, assessment of symptoms changes, and some may be flawed by potential pitfalls. Consequently, the information could be not consistent. We critically reviewed the main available trials, attempting to address future research in this field.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.