Evidence map›Paper›PMID 25095784›Full record

ArticleCancer research2014

Biomimetic tissue-engineered systems for advancing cancer research: NCI Strategic Workshop report.

Teresa K Schuessler, Xin Yi Chan, Huanhuan Joyce Chen, Kyungmin Ji, Kyung Min Park, Alireza Roshan-Ghias, Pallavi Sethi, Archana Thakur, Xi Tian, Aranzazu Villasante and 4 more

Abstract readConference Proceedings
In one paragraph

Article in Cancer research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Tissue-Engineered Model of Human Osteolytic Bone Tumor.Tissue engineering. Part C, Methods · 2017
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Flow perfusion effects on three-dimensional culture and drug sensitivity of Ewing sarcoma.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Teresa K SchuesslerDivision of Cancer Biology, National Cancer Institute, Rockville, Maryland.
Xin Yi ChanDepartment of Chemical and Biomolecular Engineering, Institute for NanoBioTechnology, Physical Sciences Oncology Center, Johns Hopkins University, Baltimore, Maryland.
Huanhuan Joyce ChenDepartment of Biomedical Engineering, Cornell University, Ithaca, New York.
Kyungmin JiDepartment of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan.
Kyung Min ParkDepartment of Chemical and Biomolecular Engineering, Institute for NanoBioTechnology, Physical Sciences Oncology Center, Johns Hopkins University, Baltimore, Maryland.
Alireza Roshan-GhiasDepartment of Biomedical Engineering, Laboratory for Stem Cells and Tissue Engineering, Columbia University, New York, New York.
Pallavi SethiDepartment of Pharmaceutical Sciences, Cancer Nanotechnology Training Center, University of Kentucky College of Pharmacy, Lexington, Kentucky.
Archana ThakurDepartment of Oncology, Karmanos Cancer Institute at Wayne State University, Detroit, Michigan.
Xi TianDepartment of Radiation Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Aranzazu VillasanteDepartment of Biomedical Engineering, Laboratory for Stem Cells and Tissue Engineering, Columbia University, New York, New York.
Ioannis K ZervantonakisDepartment of Cell Biology, Harvard Medical School, Boston, Massachusetts.
Nicole M MooreDivision of Cancer Biology, National Cancer Institute, Rockville, Maryland.
Larry A NagaharaDivision of Cancer Biology, National Cancer Institute, Rockville, Maryland.
Nastaran Z KuhnDivision of Cancer Biology, National Cancer Institute, Rockville, Maryland. nas.kuhn@nih.gov.

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Advanced technologies and biomaterials developed for tissue engineering and regenerative medicine present tractable biomimetic systems with potential applications for cancer research. Recently, the National Cancer Institute convened a Strategic Workshop to explore the use of tissue biomanufacturing for development of dynamic, physiologically relevant in vitro and ex vivo biomimetic systems to study cancer biology and drug efficacy. The workshop provided a forum to identify current progress, research gaps, and necessary steps to advance the field. Opportunities discussed included development of tumor biomimetic systems with an emphasis on reproducibility and validation of new biomimetic tumor models, as described in this report.

Indexed as

BiomimeticsTissue EngineeringHumansNeoplasms

Identifiers

PMID25095784
PMCPMC4184963

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.