Statins × lipids

SynthesisPloS one2014

Lower intensified target LDL-c level of statin therapy results in a higher risk of incident diabetes: a meta-analysis.

Rongrong Cai et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 1,000 people · 2014

Randomised comparison

Raised lipids

+33%+14% to +56%

Bigger than 6 in 10 on the map

As reported

OR 1.33, 95% CI 1.14–1.56

Range includes no effect

No clear effect on lipids

−5%−17% to +8%

Bigger than 1 in 10 on the map

As reported

OR 0.95, 95% CI 0.83–1.08

Range includes no effect

No clear effect on lipids

−1%−11% to +11%

Smaller than almost all on the map

As reported

OR 0.99, 95% CI 0.89–1.11

Three numbers in the abstract

the abstract, start to end

to placebo-controlled trials (OR 0.95, 95% CI 0.83 to 1.08,

level was lower than 1.8 mmol/L (OR 1.33, 95% CI 1.14 to 1.56;

or standard care control therapy (OR 0.99, 95% CI 0.89 to 1.11) (Figure

← favours treatmentfavours comparator →
could be chance
Lipids
OR 0.950.83–1.08
Lipids
OR 1.331.14–1.56
Lipids
OR 0.990.89–1.11
StatinsLipids

Statins × lipidshelps?mixed

unlikelylikely
0.50not counted
← favours treatmentfavours comparator →
more certainless certain
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Full record →Abstract, authors, funding and every citing paper · PMID 25122464