Evidence map›Paper›PMID 25126554›Full record

ReviewBioMed research international2014

Next generation delivery system for proteins and genes of therapeutic purpose: why and how?

Ashish Ranjan Sharma, Shyamal Kumar Kundu, Ju-Suk Nam, Garima Sharma, C George Priya Doss, Sang-Soo Lee, Chiranjib Chakraborty

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. IL-1 receptor antagonist: etiological and drug delivery systems overview.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
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  4. Article
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  7. Current Perspectives on Synthetic Compartments for Biomedical Applications.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Article
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  14. Article
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  19. Killing of cancer cells through the use of eukaryotic expression vectors harbouring genes encoding nucleases and ribonuclease inhibitor.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashish Ranjan SharmaInstitute for Skeletal Aging & Orthopedic Surgery, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.ORCID 0000-0003-3973-6755
Shyamal Kumar KunduDepartment of Physics, School of Basic and Applied Sciences, Galgotias University, Greater Noida 203201, India.ORCID 0000-0003-1538-7300
Ju-Suk NamInstitute for Skeletal Aging & Orthopedic Surgery, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.ORCID 0000-0003-4437-3194
Garima SharmaInstitute for Skeletal Aging & Orthopedic Surgery, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.ORCID 0000-0003-1763-0730
C George Priya DossMedical Biotechnology Division, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu 632014, India.
Sang-Soo LeeInstitute for Skeletal Aging & Orthopedic Surgery, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea.
Chiranjib ChakrabortyInstitute for Skeletal Aging & Orthopedic Surgery, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200704, Republic of Korea ; Department of Bioinformatics, School of Computer Sciences, Galgotias University, Greater Noida 203201, India.ORCID 0000-0002-3958-239X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins and genes of therapeutic interests in conjunction with different delivery systems are growing towards new heights. "Next generation delivery systems" may provide more efficient platform for delivery of proteins and genes. In the present review, snapshots about the benefits of proteins or gene therapy, general procedures for therapeutic protein or gene delivery system, and different next generation delivery system such as liposome, PEGylation, HESylation, and nanoparticle based delivery have been depicted with their detailed explanation.

Indexed as

Drug Delivery SystemsGenetic TherapyGene Transfer TechniquesHumansLiposomesNanoparticlesProteinsLiposomesProteins

Identifiers

PMID25126554
PMCPMC4122142

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.