Evidence map›Paper›PMID 25178286›Full record

ArticleAsian-Australasian journal of animal sciences2014

Identification of exonic nucleotide variants of the thyroid hormone responsive protein gene associated with carcass traits and Fatty Acid composition in korean cattle.

Dong-Yep Oh, Yoon-Seok Lee, Boo-Mi La, Jea-Young Lee, Yong-Soo Park, Ji-Hong Lee, Jae-Jung Ha, Jun-Koo Yi, Byung-Ki Kim, Jung-Sou Yeo

Abstract read
In one paragraph

Article in Asian-Australasian journal of animal sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Review
  4. Review
  5. Association betweenAnimals : an open access journal from MDPI · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dong-Yep OhInstitute of Green Bio Science and Technology, Seoul National University, Pyeongchang 232-916, Korea .
Yoon-Seok LeeInstitute of Green Bio Science and Technology, Seoul National University, Pyeongchang 232-916, Korea .
Boo-Mi LaSchool of Biotechnology, Yeungnam University, Gyeongsan 712-749, Korea .
Jea-Young LeeDepartment of Statistics, Yeungnam University, Gyeongsan 712-749, Korea .
Yong-Soo ParkDepartment of Equine Industry, Korea National College of Agriculture and Fisheries, Hwaseong 445-760, Korea .
Ji-Hong LeeGyeongbuk Provincial College, Yecheon 750-767, Korea .
Jae-Jung HaInstitute of Green Bio Science and Technology, Seoul National University, Pyeongchang 232-916, Korea .
Jun-Koo YiInstitute of Green Bio Science and Technology, Seoul National University, Pyeongchang 232-916, Korea .
Byung-Ki KimInstitute of Green Bio Science and Technology, Seoul National University, Pyeongchang 232-916, Korea .
Jung-Sou YeoSchool of Biotechnology, Yeungnam University, Gyeongsan 712-749, Korea .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The thyroid hormone responsive protein (THRSP) gene is a functional gene that can be used to indicate the fatty acid compositions. This study investigates the relationships of exonic single nucleotide polymorphisms (SNPs) in the THRSP gene and fatty acid composition of muscle fat and marbling score in the 612 Korean cattle. The relationships between fatty acid composition and eight SNPs in the THRSP gene (g.78 G>A, g.173 C>T, g.184 C>T, g.190 C>A, g.194 C>T, g.277 C>G, g.283 T>G and g.290 T>G) were investigated, and according to the results, two SNPs (g.78 G>A and g.184 C>T) in exon 1 were associated with fatty acid composition. The GG and CC genotypes of g.78 G>A and g.184 C>T had higher unsaturated fatty acid (UFA) and monounsaturated fatty acid (MUFA) content (p<0.05). In addition, the ht1*ht1 group (Val/Ala haplotype) in a linkage disequilibrium increased MUFAs and marbling scores for carcass traits (p<0.05). As a result, g.78 G>A and g.184 C>T had significantly relationships with UFAs and MUFAs. Two SNPs in the THRSP gene affected fatty acid composition, suggesting that GG and CC genotypes and the ht1*ht1 group (Val/Ala haplotype) can be markers to genetically improve the quality and flavor of beef.

Indexed as

Beef FlavorKorean CattleSNPThyroid Hormone Responsive Protein (THRSP) GeneUnsaturated Fatty Acid

Identifiers

PMID25178286
PMCPMC4150167

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.