← GLP-1 receptor agonists × glycemic control

TrialDiabetologia2014

HARMONY 4: randomised clinical trial comparing once-weekly albiglutide and insulin glargine in patients with type 2 diabetes inadequately controlled with metformin with or without sulfonylurea.

Peter N Weissman et al.PubMed ↗Publisher ↗

What the trial testedas reported · 779 people · 2014

Range includes no effect

No clear effect on glycemic control

+0.11percentage points−0.04 to +0.27

As reported

difference 0.11 %, 95% CI −0.04 to 0.27

Not counted

Probably lowered glycemic control

−2.61kg−3.20 to −2.02

As reported

difference −2.61 kg, 95% CI −3.20 to −2.02

Two numbers in the abstract

the abstract, start to end

… model-adjusted treatment difference of 0.11% (95% CI -0.04%, 0.27%) (1.2 …

… with a mean treatment difference of -2.61 kg (95% CI -3.20, -2.02; …

← favours treatmentfavours comparator →
could be chance
Glycemic control
0.11−0.04 to 0.27
Glycemic control
−2.61−3.20 to −2.02
GLP-1 receptor agonistsInsulinGlycemic control
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2 trials

NCT00838916phase 3779 enrolled2009NCT0319963814 enrolled2016
Full record →Abstract, authors, funding and every citing paper · PMID 25208756