ArticleSurgical endoscopy2015
Early postoperative weight loss predicts maximal weight loss after sleeve gastrectomy and Roux-en-Y gastric bypass.
Article in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 67 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
BARI-OPTIMISE: a Double-blinded, Randomised, Placebo-controlled Trial of Liraglutide 3.0 mg in Patients With Poor Weight-loss and a Suboptimal Glucagon-like Peptide-1 Response Following Bariatric Surgery
Evaluation of the Effect of a Lifestyle Intervention Compared to Usual Care on Weight Loss and Changes in Body Composition, Physical Activity Levels and Health-related Quality of Life in the First Year Following Bariatric Surgery
Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Proposed Definitions and Clinical Recommendations for the Management of Weight Recurrence, Partial Response, and Nonresponse Following Metabolic and Bariatric Surgery.Obesity surgery · 2025Pooled it
- Roux-en-Y gastric bypass, sleeve gastrectomy, or one-anastomosis gastric bypass? A systematic review and meta-analysis of randomized-controlled trials.Obesity (Silver Spring, Md.) · 2022Pooled it
- Sleeve Gastrectomy Weight Loss and the Preoperative and Postoperative Predictors: a Systematic Review.Obesity surgery · 2019Pooled it
- Exploring the Acceptability of Post-bariatric Nutritional-Behavioral and Supervised Exercise Intervention (BARI-LIFESTYLE): A Mixed Methods Evaluation.Obesity surgery · 2025Trial
- 24-Month follow-up of randomized controlled trial of guided-self-help for loss-of-control eating after bariatric surgery.The International journal of eating disorders · 2022Trial
- Randomized Controlled Trial of Treatments for Loss-of-Control Eating Following Bariatric Surgery.Obesity (Silver Spring, Md.) · 2021Trial
- Bikini Line Sleeve Gastrectomy: Initial Report.Obesity surgery · 2017Trial
- Incidence and Predictors of Suboptimal Early Weight Loss after Bariatric Procedures.Obesity surgery · 2026Article
- Association of Rapid Early Weight Loss with One-Year Hepatic Steatosis Improvement After Sleeve Gastrectomy: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Early prediction of suboptimal clinical response after bariatric surgery using total weight loss percentiles.Scientific reports · 2025Article
- Baseline metabolomic profile as potential biomarker for weight change after Roux-en-Y gastric bypass (RYGB) surgery.Research square · 2025Article
- Preoperative Tyrosine Levels as Predictive Biomarkers for Excessive Fat-Free Mass Loss Following Laparoscopic Sleeve Gastrectomy in Patients with Morbid Obesity.Metabolites · 2025Article
- Clinical Significance of Early Postoperative Weight Loss in Bariatric Surgery: A Narrative Review.Journal of metabolic and bariatric surgery · 2025Review
- Critical Time Points for Assessing Long-Term Clinical Response After Sleeve Gastrectomy-A Retrospective Study of Patients with 13-Year Follow-Up.Obesity surgery · 2025Article
- Metabolic and bariatric surgery outcomes in adolescents: a single center's seven-year update.Surgical endoscopy · 2024Article
- Article
- Plasma SHBG Levels as an Early Predictor of Response to Bariatric Surgery.Obesity surgery · 2024Article
- Enhanced Patient Portal Engagement Associated with Improved Weight Loss Outcomes in Post-Bariatric Surgery Patients.medRxiv : the preprint server for health sciences · 2024Article
- Establishment of a novel weight reduction model after laparoscopic sleeve gastrectomy based on abdominal fat area.Frontiers in surgery · 2024Article
- How to address weight regain after bariatric surgery in an individualized way.Reviews in endocrine & metabolic disorders · 2023Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies show that 'poor responders' to Roux-en-Y gastric bypass (RYGBP) may be identified on the basis of early postoperative weight loss. Early identification of poor responders could allow earlier provision of postoperative behavioural and/or intensive lifestyle interventions and enhance their maximal weight loss. Our aim was to investigate whether early postoperative weight loss predicts the maximal weight loss response after RYGBP and sleeve gastrectomy (SG).
methodsWe undertook a retrospective cross-sectional study of 1,456 adults who underwent either RYGBP (n = 918) or SG (n = 538) as a primary procedure in one of two European centres. Postoperative weight loss was expressed as weight loss velocity (WLV) and percentage weight loss. Linear regression analyses were performed to determine the association of early postoperative weight loss with maximal %WL, including adjustment for baseline variables.
resultsThere was marked variability in maximal %WL following both RYGBP (mean 32.9 %, range 4.1-60.9 %) and SG (mean 26.2 %, range 1.1-58.3 %). WLV 3-6 months postoperatively was more strongly associated with maximal %WL (r (2) = 0.32 for RYGBP and r (2) = 0.26 for SG, P < 0.001 for both) than either WLV 0-6 weeks or 6 weeks to 3 months postoperatively (r (2) = 0.14 and 0.10 for RYGBP, respectively; r (2) = 0.18 and 0.21 for SG, respectively; P < 0.001 for all). Multiple linear regression analysis, including baseline variables of age, sex, preoperative BMI, type 2 diabetes, ethnicity, and bariatric centre, revealed that 3-6 month WLV was an independent predictor of maximal %WL in both SG and RYGBP groups (standardised β-coefficients 0.51 and 0.52, respectively; P < 0.001 for both).
conclusionsThere is a marked variability in weight loss response following RYGBP and SG. Early postoperative weight loss can be used to identify patients whose predicted weight loss trajectories are suboptimal. Early targeting of poor responders with more intensive postoperative lifestyle and behavioural support could potentially enhance their weight loss response.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.