Evidence map›Paper›PMID 25296016›Full record

ArticleComparative medicine2014

Novel cuff design to facilitate anastomosis of small vessels during cervical heterotopic heart transplantation in rats.

Tathyana F Fensterer, Cynthia J Miller, Gustavo Perez-Abadia, Claudio Maldonado

Open access · greenAbstract read
In one paragraph

Article in Comparative medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tathyana F FenstererDepartment of Surgery, University of Louisville, Louisville, Kentucky, USA.
Cynthia J MillerDepartment of Physiology and Biophysics, University of Louisville, Louisville, Kentucky, USA.
Gustavo Perez-AbadiaDepartment of Physiology and Biophysics, University of Louisville, Louisville, Kentucky, USA.
Claudio MaldonadoDepartments of Surgery, Physiology and Biophysics, University of Louisville, Louisville, Kentucky, USA. cjmald01@louisville.edu.
University of Louisville · US

Funding

New anti-complement therapy to reduce reperfusion injury: Phase IIR42HL079855 · NHLBI · ENDOPROTECH, INC. · PI MALDONADO, CLAUDIO · 2008 to 2009
$964k
NHLBI NIH HHS R42 HL079855NHLBI NIH HHS R42HL079855
6 · The paper itself

Abstract

Cervical heterotopic heart transplantation in rodents is a useful tool for studying transplantation immunology. However, end-to-end anastomosis of small-diameter vessels by using standard microsurgical technique is technically difficult and can require prolonged graft ischemia. A novel cuff system was designed from polyethylene tubing to allow anastomosis of vessels with internal luminal diameters of 0.3 to 0.9 mm. Key features include a spring-like adjustable lumen to facilitate vessel eversion, a barb to hold vessel ends in place after eversion, and a handling system that allows easy manipulation and stabilization of cuffs by a single operator. After a training period, a single operator performed a series of 8 transplants in which the mean warm ischemic time of grafts was 8.5 ± 2.9 min. Here we provide a detailed description of how to construct and perform end-to-end vessel anastomosis by using our novel cuff system. The discussion of the technique is supplemented with tips learned during the process of developing a reliable experimental model.

Indexed as

Surgical EquipmentAnastomosis, SurgicalAnimalsBlood VesselsEquipment DesignGraft SurvivalHeart TransplantationLearning CurveMaleModels, AnimalMotor SkillsPolyethyleneRats, Inbred F344Time FactorsTransplantation, HeterotopicVascular Surgical ProceduresPolyethylene

Identifiers

PMID25296016
PMCPMC4170094
OpenAlexW1706741056

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.