Observational studyCardiovascular diabetology2014
Plasma triglycerides predict ten-years all-cause mortality in outpatients with type 2 diabetes mellitus: a longitudinal observational study.
Observational study in Cardiovascular diabetology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dietary program and physical activity impact on biochemical markers in patients with type 2 diabetes: A systematic review.Atencion primaria · 2018Pooled it
- Trial
- Liraglutide improves metabolic parameters and carotid intima-media thickness in diabetic patients with the metabolic syndrome: an 18-month prospective study.Cardiovascular diabetology · 2016 · on this mapTrial
- Fasting Triglycerides in the Upper Normal Range Are Independently Associated with an Increased Risk of Diabetes Mortality in a Large Representative US Population.Journal of cardiovascular development and disease · 2024Article
- The Impact of Statin Therapy on Cardiovascular Outcomes in Patients With Diabetes: A Systematic Review.Cureus · 2023Review
- Atherosclerosis indexes and incident T2DM in middle-aged and older adults: evidence from a cohort study.Diabetology & metabolic syndrome · 2023Article
- Lipoproteins and Cardiovascular Disease: An Update on the Clinical Significance of Atherogenic Small, Dense LDL and New Therapeutical Options.Biomedicines · 2021Article
- Independent association of atherogenic dyslipidaemia with all-cause mortality in individuals with type 2 diabetes and modifying effect of gender: a prospective cohort study.Cardiovascular diabetology · 2021Observational
- Application of Differential Network Enrichment Analysis for Deciphering Metabolic Alterations.Metabolites · 2020Article
- Increased residual cardiovascular risk in patients with diabetes and high versus normal triglycerides despite statin-controlled LDL cholesterol.Diabetes, obesity & metabolism · 2019Article
- Triglyceride glucose index for predicting cardiovascular outcomes in patients with coronary artery disease.Journal of thoracic disease · 2018Article
- Diabetes classification model based on boosting algorithms.BMC bioinformatics · 2018Article
- The association of triglycerides and total cholesterol concentrations with newly diagnosed diabetes in adults in China.Oncotarget · 2017Article
- Potential Association of Triglyceride Glucose Index with Cardiac Autonomic Neuropathy in Type 2 Diabetes Mellitus Patients.Journal of Korean medical science · 2017Article
- Changes in triglycerides and high-density lipoprotein cholesterol may precede peripheral insulin resistance, with 2-h insulin partially mediating this unidirectional relationship: a prospective cohort study.Cardiovascular diabetology · 2016Article
- Cholesterol remnants and triglycerides are associated with decreased myocardial function in patients with type 2 diabetes.Cardiovascular diabetology · 2016Article
- Mortality and causes of death in a national sample of type 2 diabetic patients in Korea from 2002 to 2013.Cardiovascular diabetology · 2016Article
- Atherogenic dyslipidemia and risk of silent coronary artery disease in asymptomatic patients with type 2 diabetes: a cross-sectional study.Cardiovascular diabetology · 2016Article
- Determinants of mortality in patients with type 2 diabetes: a review.Reviews in endocrine & metabolic disorders · 2016Review
- The association of physical activity and cholesterol concentrations across different combinations of central adiposity and body mass index.Health promotion perspectives · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular disease (CVD) is the leading cause of death in type 2 diabetes mellitus (T2DM). American Diabetes Association standards of care set a series of targets recommended for the CVD prevention: blood pressure, LDL and HDL cholesterol (LDL-C and HDL-C), triglycerides and HbA1c goals. The aim of this study was to evaluate cardiovascular risk factors in a T2DM outpatient population in order to estimate their specific clinical value in predicting long-term overall mortality.
methodsOur study population was composed of 1917 T2DM outpatients attending the hospital-based Diabetes Clinic of Ferrara for a mean follow-up period of 10 years; recorded information included personal, clinical and biochemical data, and pharmacological treatment.
resultsA Cox proportional hazard analysis was performed, pointing out as age (HR:1.08; IC95%: 1.06-1.11), sex (males: HR:1.97; IC95%: 1.26-3.07), mean triglycerides levels during follow-up (III vs I tertile: HR:1.87; IC95%: 1.12-3.12) and lipid-lowering treatment (HR:0.56; IC95%: 0.35-0.90) were significantly associated with all-cause mortality, independent of confounding factors such as mean values of LDL-C, HDL-C, HbA1c, blood pressure, BMI, fasting glucose, and antihypertensive and antidiabetic treatment.
conclusionsThis finding suggests that more attention should be given to the management of cardiovascular risk in type 2 diabetic patients with high triglycerides levels.
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