ArticleLipids in health and disease2014
Low HDL cholesterol is correlated to the acute ischemic stroke with diabetes mellitus.
Article in Lipids in health and disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- The correlation between the uric acid to high-density lipoprotein cholesterol ratio and stroke.Frontiers in medicine · 2025Article
- In Mild and Moderate Acute Ischemic Stroke, Increased Lipid Peroxidation and Lowered Antioxidant Defenses Are Strongly Associated with Disabilities and Final Stroke Core Volume.Antioxidants (Basel, Switzerland) · 2023Article
- Relationship between lipoproteins, thrombosis, and atrial fibrillation.Cardiovascular research · 2022Review
- Inverse Association between High-Density Lipoprotein Cholesterol and Adverse Outcomes among Acute Ischemic Stroke Patients with Diabetes Mellitus.Biomedicines · 2021Article
- A cohort study on risk factors of high-density lipoprotein cholesterol hypolipidemia among urban Chinese adults.Lipids in health and disease · 2021Article
- Immune-inflammatory, oxidative stress and biochemical biomarkers predict short-term acute ischemic stroke death.Metabolic brain disease · 2019Article
- Relationship between White Matter Hyperintensities and Hematoma Volume in Patients with Intracerebral Hematoma.Aging and disease · 2018Article
- Dyslipidaemia was correlated to the posterior circulation infarction in non-diabetic populations.Lipids in health and disease · 2018Article
- Progression of White Matter Hyperintensities Contributes to Lacunar Infarction.Aging and disease · 2018Article
- Association of Rs2071410 on Furin with Transient Ischemic Attack Susceptibility and Prognosis in a Chinese Population.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo clarify the role of lipid composition in the occurrence of acute ischemic stroke (AIS) with diabetes mellitus (DM) and its influence factors.
methodsData was collected from the patients hospitalization in Affiliated Drum Tower Hospital of Nanjing University Medical School from October 2008 to May 2012, which included AIS and non-AIS consist of transient ischemic attack (TIA) and Vertigo or dizzy. Lipid and other risk factors including blood glucose (BG), uric acid (UA), hypertension, DM and atrial fibrillation (AF) were investigated in relation to occurrence of AIS.
resultsThe level of high density lipoprotein (HDL) cholesterol was decreased obviously in the DM group compared to the non-DM group and low level of HDL cholesterol was prevalent in the AIS patients with DM. logistic regression demonstrated that decreased HDL cholesterol was correlated to the AIS with DM, not all AIS, and the relative risk of ischemic stroke in low HDL cholesterol level group was 2.113 (95% CI = 1.191-3.749, P = 0.011) compared to the high level group. Furthermore, age has the obviously impact on it. HDL cholesterol was correlated to the AIS with DM just in the populations of aged ≦70 years (OR = 0.192, P = 0.000), low level of HDL cholesterol had more high risk of ischemic stroke than that in the high level group (OR = 6.818, P = 0.002).
conclusionDecreased HDL cholesterol was correlated to the occurrence of AIS with DM, especially in the populations of aged ≦70 years.
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