SynthesisPediatric research2015
Kidney disease among children in sub-Saharan Africa: systematic review.
Synthesis in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- Prevalence, predictors and outcomes of renal dysfunction among children with malignancy on chemotherapy at tertiary hospitals in Tanzania.BMC pediatrics · 2026Article
- Risks, Diagnostic Thresholds, and Outcomes of Pediatric CKD in Rural Africa.Kidney international reports · 2025Article
- UrogenitalOpen forum infectious diseases · 2025Article
- Assessing the Effects of One-Time Praziquantel Treatment on Urogenital Lesions Detected by Ultrasound in Schistosoma haematobium-Infected Individuals in Chad.The American journal of tropical medicine and hygiene · 2024Article
- Better Together: acceptability, feasibility and preliminary impact of chronic illness peer support groups for South African adolescents and young adults.Journal of the International AIDS Society · 2023Article
- Burden of Paediatric Kidney Diseases in a Tertiary Care Hospital in Harare, Zimbabwe.Clinical medicine insights. Pediatrics · 2023Article
- Forgotten but not gone in rural South Africa: Urinary schistosomiasis and implications for chronic kidney disease screening in endemic countries.Wellcome open research · 2023Article
- Renal Papillary Necrosis (RPN) in an African Population: Disease Patterns, Relevant Pathways, and Management.Biomedicines · 2022Review
- Malaria-Associated Acute Kidney Injury in African Children: Prevalence, Pathophysiology, Impact, and Management Challenges.International journal of nephrology and renovascular disease · 2021Review
- Challenges of access to kidney care for children in low-resource settings.Nature reviews. Nephrology · 2021Review
- Methods to estimate baseline creatinine and define acute kidney injury in lean Ugandan children with severe malaria: a prospective cohort study.BMC nephrology · 2020Article
- Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study.Annals of global health · 2020Article
- Renal abnormalities and its associated factors among school-aged children living inTropical medicine and health · 2020Article
- Association Between Perfluoroalkyl Substance Exposure and Renal Function in Children With CKD Enrolled in H3Africa Kidney Disease Research Network.Kidney international reports · 2019Article
- Prevalence and factors associated with renal dysfunction in children admitted to two hospitals in northwestern Tanzania.BMC nephrology · 2019Article
- Proteinuric kidney disease in children at Queen Elizabeth Central Hospital, Malawi.BMC nephrology · 2018Article
- Reducing major risk factors for chronic kidney disease.Kidney international supplements · 2017Review
- Inequalities in access to pediatric ESRD care: a global health challenge.Pediatric nephrology (Berlin, Germany) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
The global burden of kidney disease is increasing, and several etiologies first begin in childhood. Risk factors for pediatric kidney disease are common in Africa, but data regarding its prevalence are lacking. We completed a systematic review of community-based studies describing the prevalence of proteinuria, hematuria, abnormal imaging, or kidney dysfunction among children in sub-Saharan Africa (SSA). Medline and Embase were searched. Five hundred twenty-three references were reviewed. Thirty-two references from nine countries in SSA were included in the qualitative synthesis. The degree of kidney damage and abnormal imaging varied widely: proteinuria 32.5% (2.2-56.0%), hematuria 31.1% (0.6-67.0%), hydronephrosis 11.3% (0.0-38.0%), hydroureter 7.5% (0.0-26.4%), and major kidney abnormalities 0.1% (0.0-0.8%). Serum creatinine was reported in four studies with insufficient detail to identify the prevalence renal dysfunction. A majority of the studies were performed in Schistosoma haematobium endemic areas. A lower prevalence of kidney disease was observed in the few studies from nonendemic areas. Published data on pediatric kidney disease in SSA are highly variable and dependent on S. haematobium prevalence. More community-based studies are needed to describe the burden of pediatric kidney disease, particularly in regions where S. haematobium infection is nonendemic.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.