ReviewSleep medicine reviews2015
Sleep, sleep disturbance, and fertility in women.
Review in Sleep medicine reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07343947 (Melatonin Supplementation in Ovarian Response), which is not on this map. Cited by 101 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Melatonin Supplementation in Ovarian Response: a Double-blind Randomized Controlled Trial on Follicular Fluid Melatonin Levels and Reproductive Outcomes in Infertile Women
Who cites it
101 citing papers in PubMed, 10 syntheses or guidelines pooled it, 221 citations in OpenAlex.
- The Association Between Sleep Duration and the Risk of Hypertension: A Systematic Review and Meta-analysis of Cohort Studies.Journal of general internal medicine · 2025Pooled it
- Assessment of ovarian dysfunction induced by environmental toxins: a systematic review.Frontiers in public health · 2025Pooled it
- Sleep disturbances and female infertility: a systematic review.BMC women's health · 2024Pooled it
- Sleep disturbance and its associated factors among pregnant women in Ethiopia: systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Infertility and cortisol: a systematic review.Frontiers in endocrinology · 2023Pooled it
- Sleep disturbances, sleep quality, and cardiovascular risk factors in women with polycystic ovary syndrome: Systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Effects of physical activity and sleep duration on fertility: A systematic review and meta-analysis based on prospective cohort studies.Frontiers in public health · 2022Pooled it
- Associations of plasma hypocretin-1 with metabolic and reproductive health: Two systematic reviews of clinical studies.Sleep medicine reviews · 2020Pooled it
- Psychological aspects of infertility. A systematic review.The Journal of international medical research · 2020Pooled it
- The prevalence of obstructive sleep apnoea in women with polycystic ovary syndrome: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2020Pooled it
- Sleep Habits of Women With Infertility.The Journal of clinical endocrinology and metabolism · 2021Trial
- Mediating role of sleep disorders in the association between depression and infertility: A cross-sectional study using the National Health and nutrition examination survey.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Impaired sleep quality and mental health are associated with the severity of menopausal symptoms.Physical activity and nutrition · 2026Article
- Associations between daytime napping and parameters of ovarian reserve among women undergoing assisted reproductive technology.BMC women's health · 2026Article
- Ovarian Rev-erbα: a central regulator of fertility following chronodisruption.Frontiers in endocrinology · 2026Article
- Sleep Disruption and Shift Work Associate with Increased Risk of Reproductive Endocrine Disorders: Evidence from UK Biobank and Mendelian Randomization.International journal of women's health · 2026Article
- Clinical characteristics and pregnancy outcomes in polycystic ovary syndrome complicated by obstructive sleep apnea: a correlative study.Frontiers in medicine · 2026Article
- Dysfunctional decidual CD2Frontiers in immunology · 2026Article
- Determining the relationship between sleep quality and reproductive health issues in fertile and infertile men and women: A cross-sectional study.Sleep medicine: X · 2025Article
- Longitudinal associations between maternal sleep, anxiety, depression across pregnancy trimesters and adverse pregnancy outcomes: a prospective cohort study.Reproductive health · 2025Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Sleep and sleep disturbances are increasingly recognized as determinants of women's health and well-being, particularly in the context of the menstrual cycle, pregnancy, and menopause. At present, however, little is known about whether fertility is affected by sleep quantity and quality. That is, to what degree, and by what mechanisms, do sleep and/or its disturbances affect fertility? The purpose of this review is to synthesize what is known about sleep disturbances in relation to reproductive capacity. A model is provided, whereby stress, sleep dysregulation, and circadian misalignment are delineated for their potential relevance to infertility. Ultimately, if it is the case that sleep disturbance is associated with infertility, new avenues for clinical intervention may be possible.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.