Evidence map›Paper›PMID 25468936›Full record

ReviewDevelopment (Cambridge, England)2014

Transcription factors and effectors that regulate neuronal morphology.

Celine Santiago, Greg J Bashaw

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Regulatory logic of neuronal differentiation in theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Concordant transcriptional and morphological remodeling revealed bybioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Regulatory logic of neuronal identity specification inbioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Transcriptional regulation of neuronal identity.The European journal of neuroscience · 2022
    Review
  18. Article
  19. Article
  20. The regulatory landscape of neurite development inFrontiers in molecular neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Celine SantiagoDepartment of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Greg J BashawDepartment of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA gbashaw@mail.med.upenn.edu.

Funding

Robo receptor signaling and regulation during axon guidance in DrosophilaR01NS046333 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BASHAW, GREG J. · 2003 to 2016
$3.9M
Transcriptional mechanisms coordinating midline and motor axon guidanceR01NS054739 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI BASHAW, GREG J. · 2008 to 2016
$2.4M
NINDS NIH HHS R01 NS046333NINDS NIH HHS R01 NS054739
6 · The paper itself

Abstract

Transcription factors establish the tremendous diversity of cell types in the nervous system by regulating the expression of genes that give a cell its morphological and functional properties. Although many studies have identified requirements for specific transcription factors during the different steps of neural circuit assembly, few have identified the downstream effectors by which they control neuronal morphology. In this Review, we highlight recent work that has elucidated the functional relationships between transcription factors and the downstream effectors through which they regulate neural connectivity in multiple model systems, with a focus on axon guidance and dendrite morphogenesis.

Indexed as

Models, NeurologicalAnimalsAxonsDendritesGene Expression Regulation, DevelopmentalHumansNeurogenesisNeuronsReceptors, Cell SurfaceTranscription FactorsReceptors, Cell SurfaceTranscription FactorsAxon guidanceDendritic morphologyLateral positionMidline crossingMotor neuronsTranscription factors

Identifiers

PMID25468936
PMCPMC4299270

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.