Evidence map›Paper›PMID 25504286›Full record

ArticleGenetic epidemiology2015

Genetic data simulators and their applications: an overview.

Bo Peng, Huann-Sheng Chen, Leah E Mechanic, Ben Racine, John Clarke, Elizabeth Gillanders, Eric J Feuer

Abstract read
In one paragraph

Article in Genetic epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  5. Article
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  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. isqg: A Binary Framework forG3 (Bethesda, Md.) · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. GESDB: a platform of simulation resources for genetic epidemiology studies.Database : the journal of biological databases and curation · 2016
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bo PengDepartment of Bioinformatics and Computational Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas, United States of America.
Huann-Sheng Chen
Leah E Mechanic
Ben Racine
John Clarke
Elizabeth Gillanders
Eric J Feuer

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Statistical Methods for Population Genomics and "Next-gen" Sequencing DataR01HG005859 · NHGRI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SCHEET, PAUL A · 2011 to 2015
$1.9M
NCI NIH HHS P30 CA016672NHGRI NIH HHS 1R01HG005859NHGRI NIH HHS R01 HG005859PHS HHS HHSN261201100558P
6 · The paper itself

Abstract

Computer simulations have played an indispensable role in the development and applications of statistical models and methods for genetic studies across multiple disciplines. The need to simulate complex evolutionary scenarios and pseudo-datasets for various studies has fueled the development of dozens of computer programs with varying reliability, performance, and application areas. To help researchers compare and choose the most appropriate simulators for their studies, we have created the genetic simulation resources (GSR) website, which allows authors of simulation software to register their applications and describe them with more than 160 defined attributes. This article summarizes the properties of 93 simulators currently registered at GSR and provides an overview of the development and applications of genetic simulators. Unlike other review articles that address technical issues or compare simulators for particular application areas, we focus on software development, maintenance, and features of simulators, often from a historical perspective. Publications that cite these simulators are used to summarize both the applications of genetic simulations and the utilization of simulators.

Indexed as

Computer SimulationModels, GeneticSoftwareModels, StatisticalReproducibility of Resultsgenetic simulationgenetic simulation resourcessoftware

Identifiers

PMID25504286
PMCPMC4804465

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.