Evidence map›Paper›PMID 25526726›Full record

ReviewEuropean heart journal2015

Acute myocardial infarction with no obstructive coronary atherosclerosis: mechanisms and management.

Giampaolo Niccoli, Giancarla Scalone, Filippo Crea

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in European heart journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05122780 (PROgnostic Value of Precision Medicine in Patients With Myocardial Infarction and Non-obStructive Coronary artEries), which is not on this map. Cited by 126 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05122780 phase4unknown statusstarted 2021, after this paper: background citation

PROgnostic Value of Precision Medicine in Patients With Myocardial Infarction and Non-obStructive Coronary artEries: the PROMISE Trial.

Ran2021Enrolled120Registered outcomes17Posted comparisons0ConditionsMyocardial Infarction With Non-Obstructive Coronary ArteriesArmsACEi/ARB, Acetylcholine provocative test, Anticoagulant, Antiplatelet Drug, Beta Blocker
PMID 30913893PMID 25587100PMID 26576922PMID 28179398PMID 24847016PMID 28239487PMID 24071763PMID 24046434PMID 1825037PMID 28476516PMID 28624816PMID 29228159other papers from this trial
Open the trial in the graph
3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  15. Antithrombotic Therapy for Acute Coronary Syndrome.Journal of neuroendovascular therapy · 2025
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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giampaolo NiccoliInstitute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, Rome 00168, Italy gniccoli73@hotmail.it.
Giancarla ScaloneInstitute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, Rome 00168, Italy Department of Cardiology, Thorax Institute, IDIBAPS: Institut d'Investigacions Biomediques Agust Pi i Sunyer, Hospital Clinic, Barcelona, Spain.
Filippo CreaInstitute of Cardiology, Catholic University of the Sacred Heart, Largo Agostino Gemelli, 8, Rome 00168, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) with no obstructive coronary atherosclerosis (MINOCA) is a syndrome with different causes. Its prevalence ranges between 5 and 25% of all MIs. The prognosis is extremely variable, depending on the causes of MINOCA. Clinical history, echocardiography, coronary angiography, and left ventriculography represent the first-level diagnostic investigations. Nevertheless, additional tests are required in order to establish its specific cause, thus allowing an appropriate risk stratification and treatment. We review pathogenesis, diagnosis, prognosis, and therapy of MINOCA and propose an algorithm for its management.

Indexed as

Coronary VasospasmDiagnosis, DifferentialDiagnostic Techniques, CardiovascularEmbolismHumansMyocardial InfarctionMyocarditisPlaque, AtheroscleroticPrognosisRisk FactorsRupture, SpontaneousTakotsubo CardiomyopathyVascular RemodelingAcute myocardial infarctionNo obstructive coronary atherosclerosis

Identifiers

PMID25526726

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.