ArticleDiabetes care2015
Corneal confocal microscopy shows an improvement in small-fiber neuropathy in subjects with type 1 diabetes on continuous subcutaneous insulin infusion compared with multiple daily injection.
Registry-linked trialAbstract readComparative StudyLetter
In one paragraph
Article in Diabetes care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02879409 (Does Glycated Hemoglobin Variability in Type 2 Diabetes Differ Depending on the Diabetes Treatment Threshold Used in the Qatari Population), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Does Glycated Hemoglobin Variability in Type 2 Diabetes Differ Depending on the Diabetes Treatment Threshold Used in the Qatari Population: Implication on Diabetes Complication Risk?
PMID 9742977PMID 19092145PMID 16004665PMID 9886743PMID 9742976PMID 9732337PMID 8455366PMID 8366922PMID 7997705PMID 24812434PMID 22580991PMID 2106931other papers from this trial
Open the trial in the graphWho cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- CornealFrontiers in medicine · 2022Pooled it
- Insulin resistance limits corneal nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control.Journal of diabetes investigation · 2021Trial
- Using corneal confocal microscopy to compare Mecobalamin intramuscular injections vs oral tablets in treating diabetic peripheral neuropathy: a RCT.Scientific reports · 2021Trial
- In Vivo Confocal Microscopy of the Cornea in Diagnosing Small Fibre Neuropathy: A Cross-Sectional Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
- The impact of insulin pump therapy compared to multiple daily injections on complications and mortality in type 1 diabetes: A real-world retrospective cohort study.Diabetes, obesity & metabolism · 2025Article
- Issues and challenges in diabetic neuropathy management: A narrative review.World journal of diabetes · 2023Review
- Corneal Confocal Microscopy as a Quantitative Imaging Biomarker of Diabetic Peripheral Neuropathy: A Review.Journal of clinical medicine · 2022Review
- Using Corneal Confocal Microscopy to Identify Therapeutic Agents for Diabetic Neuropathy.Journal of clinical medicine · 2022Article
- Corneal Confocal Microscopy Identifies People with Type 1 Diabetes with More Rapid Corneal Nerve Fibre Loss and Progression of Neuropathy.Journal of clinical medicine · 2022Article
- Is Nerve Electrophysiology a Robust Primary Endpoint in Clinical Trials of Treatments for Diabetic Peripheral Neuropathy?Diagnostics (Basel, Switzerland) · 2022Review
- Corneal Confocal Microscopy and the Nervous System: Introduction to the Special Issue.Journal of clinical medicine · 2022Article
- Small Nerve Fiber Damage and Langerhans Cells in Type 1 and Type 2 Diabetes and LADA Measured by Corneal Confocal Microscopy.Investigative ophthalmology & visual science · 2021Article
- Bariatric surgery leads to an improvement in small nerve fibre damage in subjects with obesity.International journal of obesity (2005) · 2021Article
- Diabetic Corneal Neuropathy.Journal of clinical medicine · 2020Review
- Corneal confocal microscopy compared with quantitative sensory testing and nerve conduction for diagnosing and stratifying the severity of diabetic peripheral neuropathy.BMJ open diabetes research & care · 2020Article
- A Systematic Review of Pharmacologic and Rehabilitative Treatment of Small Fiber Neuropathies.Diagnostics (Basel, Switzerland) · 2020Review
- A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation.Diagnostics (Basel, Switzerland) · 2020Review
- Eye care providers' emerging roles in early detection of diabetes and management of diabetic changes to the ocular surface: a review.BMJ open diabetes research & care · 2020Review
- Scientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy: A Review.JAMA neurology · 2019Article
- Early nerve fibre regeneration in individuals with type 1 diabetes after simultaneous pancreas and kidney transplantation.Diabetologia · 2019Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Shazli AzmiCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Maryam FerdousiCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Ioannis N PetropoulosCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K. Weill Cornell Medical College in Qatar, Doha, Qatar.
Georgios PonirakisCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K. Weill Cornell Medical College in Qatar, Doha, Qatar.
Hassan FadaviCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Mitra TavakoliCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Uazman AlamCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Wendy JonesCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Andrew MarshallDepartment of Clinical Neurophysiology, Central Manchester National Health Services Foundation Trust, Manchester, U.K.
Maria JeziorskaCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Andrew J M BoultonCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K.
Nathan EfronInstitute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
Rayaz A MalikCentre for Endocrinology and Diabetes, Institute of Human Development, University of Manchester and Central Manchester National Health Services Foundation Trust, Manchester Academic Health Science Centre, Manchester, U.K. Weill Cornell Medical College in Qatar, Doha, Qatar ram2045@qatar-med.cornell.edu rayaz.a.malik@manchester.ac.uk.
Weill Cornell Medical College in Qatar · QAQueensland University of Technology · AU
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Blood PressureBody Mass IndexCase-Control StudiesCholesterol, HDLCholesterol, LDLDiabetes Mellitus, Type 1Diabetic NeuropathiesErythromelalgiaGlycated HemoglobinHumansInfusions, SubcutaneousInsulinMicroscopy, ConfocalMiddle AgedNerve FibersCholesterol, HDLCholesterol, LDLGlycated HemoglobinInsulin
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
NCT02879409ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.