ReviewCurrent opinion in organ transplantation2015
Simultaneous pancreas and kidney transplantation: current trends and future directions.
Review in Current opinion in organ transplantation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- Pooled it
- Differential Oral Absorption Pharmacokinetics of Tacrolimus in Simultaneous Kidney-Pancreas Transplant Compared to Kidney Transplant Recipients.Clinical pharmacokinetics · 2026Observational
- Predictive Value of HLA-Derived T-Cell Epitope and B-Cell Epitope Matching Algorithms for Pancreas Transplant Outcomes.Clinical transplantation · 2026Article
- Simultaneous Pancreas and Kidney Transplant Recipients From Pediatric Donors Have Comparable Outcomes to Those From Adult Donors, Regardless of the Type of Donation.Transplantation direct · 2026Article
- Phase-specific intraoperative glycemic control in simultaneous pancreas-kidney transplantation.World journal of transplantation · 2026Review
- Simultaneous kidney and pancreas transplantation: Current trends and challenges.World journal of transplantation · 2026Review
- Organoid Technology as a Promising Frontier in Organ Transplantation and Regenerative Medicine.International journal of stem cells · 2026Review
- Five Decades of Pancreas Transplantation at the University Hospital of Zurich-A Story of Continuous Improvement and Success.Clinical transplantation · 2025Article
- Progressive Hyperglycemia in Tolerant Miniature Swine Recipients of Composite Islet-kidney Grafts Is not due to Islet Loss but Rather to Increased Insulin Demand With Growth.Transplantation · 2025Article
- Differentiation to insulin-positive cells from human amnion epithelial cells using a pancreatic development mimicry protocol.Histochemistry and cell biology · 2025Article
- Kidney Delayed Graft Function in Simultaneous Pancreas-Kidney Transplant Recipients Is Associated With Inferior Outcomes.Transplantation direct · 2025Article
- Predicted Indirectly Recognizable T-cell Epitope (PIRCHE) Load Correlates With Rejection Events After Simultaneous Pancreas-Kidney Transplantation.Transplantation direct · 2025Article
- Death and Graft Loss in Simultaneous Pancreas-Kidney Recipients by Donor-Recipient Cytomegalovirus Serostatus in the United States.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Article
- Different biopsy techniques for different pancreas graft locations after homolateral simultaneous pancreas-kidney transplantation.Gland surgery · 2023Article
- Comparison of Outcomes and Survival of Two Cohorts of Patients with Simultaneous Pancreas-Kidney Transplantation: A Retrospective Cohort Study in a Latin American Hospital.BioMed research international · 2023Observational
- Outcomes of Primary Simultaneous Pancreas-kidney Transplants by Induction Agent in the United States.Transplantation direct · 2022Article
- Comparison of color Doppler ultrasonography and computed tomography angiography (CTA) and computed tomography venography (CTV) in the diagnosis of arteriovenous thrombosis after simultaneous pancreas-kidney transplantation: a retrospective diagnostic accuracy study.Annals of translational medicine · 2022Article
- Nursing of acute graft-versus-host disease after simultaneous pancreas-kidney transplantation: a case series study.Gland surgery · 2022Article
- Single center results of simultaneous pancreas-kidney transplantation in patients with type 2 diabetes.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewImportant trends are being observed in pancreas transplantation in the USA. We will describe recent trends in simultaneous pancreas kidney (SPK) transplantation related to immunosuppression, treatment of rejection, and transplantation for patients of advanced age and C-peptide positive diabetes. RECENT
findingsRates of pancreas transplantation have declined, despite improved pancreatic graft outcomes. Regarding immunosuppression, trends in SPK transplantation include T-cell depletion induction therapy, waning mammalian target of rapamycin inhibitor use and steroid use in greater than 50% of pancreas transplant recipients with few patients undergoing late steroid weaning. Rejection of the pancreas may be discordant with the kidney after SPK and there is a greater appreciation of antibody-mediated rejection of the pancreas allograft. De-novo donor-specific antibody without graft dysfunction remains an active area of study, and the treatment for this condition is unclear. SPKs are being performed with greater frequency in type 2 diabetes mellitus patients and in patients of advanced age, with exemplary results. SUMMARY: The current state of the art in SPK transplantation is yielding superb and improving results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.