Evidence map›Paper›PMID 25568947›Full record

ArticlePloS one2015

Variable frequency of plastid RNA editing among ferns and repeated loss of uridine-to-cytidine editing from vascular plants.

Wenhu Guo, Felix Grewe, Jeffrey P Mower

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 97 citations in OpenAlex.

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  7. Organellar-genome analyses from the lycophyte genusFrontiers in plant science · 2024
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  13. Complete chloroplast genome of Austral king fernMitochondrial DNA. Part B, Resources · 2023
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  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wenhu GuoCenter for Plant Science Innovation, University of Nebraska, Lincoln, Nebraska, United States of America; School of Biological Sciences, University of Nebraska, Lincoln, Nebraska, United States of America; ACGT, Inc., Wheeling, Illinois, United States of America.
Felix GreweCenter for Plant Science Innovation, University of Nebraska, Lincoln, Nebraska, United States of America; Department of Agronomy and Horticulture, University of Nebraska, Lincoln, Nebraska, United States of America.
Jeffrey P MowerCenter for Plant Science Innovation, University of Nebraska, Lincoln, Nebraska, United States of America; Department of Agronomy and Horticulture, University of Nebraska, Lincoln, Nebraska, United States of America.
University of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distinct distribution and abundance of C-to-U and U-to-C RNA editing among land plants suggest that these two processes originated and evolve independently, but the paucity of information from several key lineages limits our understanding of their evolution. To examine the evolutionary diversity of RNA editing among ferns, we sequenced the plastid transcriptomes from two early diverging species, Ophioglossum californicum and Psilotum nudum. Using a relaxed automated approach to minimize false negatives combined with manual inspection to eliminate false positives, we identified 297 C-to-U and three U-to-C edit sites in the O. californicum plastid transcriptome but only 27 C-to-U and no U-to-C edit sites in the P. nudum plastid transcriptome. A broader comparison of editing content with the leptosporangiate fern Adiantum capillus-veneris and the hornwort Anthoceros formosae uncovered large variance in the abundance of plastid editing, indicating that the frequency and type of RNA editing is highly labile in ferns. Edit sites that increase protein conservation among species are more abundant and more efficiently edited than silent and non-conservative sites, suggesting that selection maintains functionally important editing. The absence of U-to-C editing from P. nudum plastid transcripts and other vascular plants demonstrates that U-to-C editing loss is a recurrent phenomenon in vascular plant evolution.

Indexed as

Genes, PlantAmino Acid SequenceBase Pair MismatchCytidineFernsMolecular Sequence DataNucleic Acid ConformationPlant ProteinsPlastidsRNA EditingRNA, PlantSequence AlignmentSequence Analysis, RNAUridineCytidinePlant ProteinsRNA, PlantUridine

Identifiers

PMID25568947
PMCPMC4287625
OpenAlexW2020692325

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.