Evidence map›Paper›PMID 25614206›Full record

ReviewObesity reviews : an official journal of the International Association for the Study of Obesity2015

Appetite and body weight regulation after bariatric surgery.

H Münzberg, A Laque, S Yu, K Rezai-Zadeh, H-R Berthoud

Open access · greenAbstract readReview
In one paragraph

Review in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
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  3. Observational
  4. Review
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  7. Observational
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  12. Article
  13. Food preferences after bariatric surgery: a review update.Internal and emergency medicine · 2023
    Review
  14. Review
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

H MünzbergPennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA.
A Laque
S Yu
K Rezai-Zadeh
H-R Berthoud
Louisiana State University System · USPennington Biomedical Research Center · US

Funding

Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI ROBERT A KESTERSON · 2005 to 2026
$26.5M
Neural mechanisms controlling food intake and body weight after bariatric surgeryR01DK047348 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BERTHOUD, HANS-RUDOLF · 1994 to 2018
$5.0M
Leptin and Central Control of ThermoregulationR01DK092587 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI MUENZBERG-GRUENING, HEIKE · 2012 to 2024
$3.5M
NIDDK NIH HHS 2P30 DK072476NIDDK NIH HHS DK047348NIDDK NIH HHS DK092587NIDDK NIH HHS F32DK097986NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK047348NIDDK NIH HHS R01 DK092587
6 · The paper itself

Abstract

Bariatric surgery continues to be remarkably efficient in treating obesity and type 2 diabetes mellitus and a debate has started whether it should remain the last resort only or also be used for the prevention of metabolic diseases. Intense research efforts in humans and rodent models are underway to identify the critical mechanisms underlying the beneficial effects with a view towards non-surgical treatment options. This non-systematic review summarizes and interprets some of this literature, with an emphasis on changes in the controls of appetite. Contrary to earlier views, surgery-induced reduction of energy intake and subsequent weight loss appear to be the main drivers for rapid improvements of glycaemic control. The mechanisms responsible for suppression of appetite, particularly in the face of the large weight loss, are not well understood. Although a number of changes in food choice, taste functions, hedonic evaluation, motivation and self-control have been documented in both humans and rodents after surgery, their importance and relative contribution to diminished appetite has not yet been demonstrated. Furthermore, none of the major candidate mechanisms postulated in mediating surgery-induced changes from the gut and other organs to the brain, such as gut hormones and sensory neuronal pathways, have been confirmed yet. Future research efforts should focus on interventional rather than descriptive approaches in both humans and rodent models.

Indexed as

Bariatric SurgeryFeeding BehaviorWeight LossAnimalsAppetite RegulationDisease Models, AnimalEnergy IntakeEnergy MetabolismGastrointestinal HormonesHumansMiceObesityRatsGastrointestinal HormonesAversive conditioningexecutive controlfood choicefood reward

Identifiers

PMID25614206
PMCPMC4784979
OpenAlexW2117308954

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.